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| | Progesterone-[2,3,4-13C3] Basic information |
| Product Name: | Progesterone-[2,3,4-13C3] | | Synonyms: | Progesterone-[2,3,4-13C3];Progesterone-[2,3,4-13C3] (CertiMass solution);4-Pregnene-3,20-dione-2,3,4-13C3;Progesterone-2,3,4-13C3 99 atom % 13C, 98% (CP);PROGESTERONE (2,3,4-13C3,99%) 50 UG/ML IN ACETONITRILE;PROGESTERONE (2,3,4-13C3,99%) 100 UG/ML IN ACETONITRILE;2,3,4-13C3]-Progesterone;Progesterone Impurity 41 | | CAS: | 327048-87-3 | | MF: | C21H30O2 | | MW: | 317.4887 | | EINECS: | | | Product Categories: | | | Mol File: | 327048-87-3.mol | ![Progesterone-[2,3,4-13C3] Structure](CAS/20180703/GIF/327048-87-3.gif) |
| | Progesterone-[2,3,4-13C3] Chemical Properties |
| Melting point | 128-132 °C(lit.) | | storage temp. | -20°C | | form | Solid | | color | White to off-white | | InChI | 1S/C21H30O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12,16-19H,4-11H2,1-3H3/t16-,17+,18-,19-,20-,21+/m0/s1/i8+1,12+1,15+1 | | InChIKey | RJKFOVLPORLFTN-TZDZRSEPSA-N | | SMILES | CC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=[13CH][13C](=O)[13CH2]C[C@]4(C)[C@H]3CC[C@]12C | | EPA Substance Registry System | Pregn-4-ene-3,20-dione-2,3,4-13C3 (327048-87-3) | | CAS Number Unlabeled | 57-83-0 |
| Hazard Codes | Xn | | Risk Statements | 40 | | Safety Statements | 36/37 | | WGK Germany | 3 | | Storage Class | 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects | | Hazard Classifications | Carc. 2
Lact.
Repr. 1A |
| | Progesterone-[2,3,4-13C3] Usage And Synthesis |
| Uses | Progesterone-13C3 is the 13C-labeled Progesterone. Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy. | | References | [1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. DOI:10.1177/1060028018797110
[2] Schindler AE, et al. Classification and pharmacology of progestins. Maturitas. 2003 Dec 10;46 Suppl 1:S7-S16. DOI:10.1016/j.maturitas.2003.09.014
[3] Zava DT, et al. Estrogen and progestin bioactivity of foods, herbs, and spices. Proc Soc Exp Biol Med. 1998 Mar;217(3):369-78. DOI:10.3181/00379727-217-44247
[4] Komesaroff PA, et al. Effects of wild yam extract on menopausal symptoms, lipids and sex hormones in healthy menopausal women. Climacteric. 2001 Jun;4(2):144-50. PMID:11428178
[5] Girling JE, et al. Progesterone, but not estrogen, stimulates vessel maturation in the mouse endometrium. Endocrinology. 2007 Nov;148(11):5433-41. Epub 2007 Aug 9. DOI:10.1210/en.2007-0856 |
| | Progesterone-[2,3,4-13C3] Preparation Products And Raw materials |
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