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- lipoic acid-NHS
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-
2025-06-07
- CAS:40846-94-4
- Min. Order: 5g
- Purity: >95.00%
- Supply Ability: 5g
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| | alpha-lipoic acid-NHS Basic information |
| Product Name: | alpha-lipoic acid-NHS | | Synonyms: | alpha-lipoic acid-NHS;Thioctic acid N-hydroxysuccinimide ester;lipoic acid-NHS;1,2-Dithiolane-3-pentanoic acid succinimidyl ester, 95%;N-Hydroxysuccinimidyl Lipoate;5-(1,2-Dithiolan-3-yl)pentanic Acid 2,5-Dioxopyrrolidin-1-yl Ester;2,5-Dioxopyrrolidin-1-yl 5-(1,2-Dithiolan-3-yl)pentanoate;DL-α-Lipoic Acid-NHS | | CAS: | 40846-94-4 | | MF: | C12H17NO4S2 | | MW: | 303.4 | | EINECS: | | | Product Categories: | | | Mol File: | 40846-94-4.mol |  |
| | alpha-lipoic acid-NHS Chemical Properties |
| Melting point | 95 °C | | Boiling point | 437.1±28.0 °C(Predicted) | | density | 1.36±0.1(20.0000℃) | | solubility | Soluble in DMSO, DMF, DCM | | form | powder to crystal | | color | White to Yellow to Orange |
| | alpha-lipoic acid-NHS Usage And Synthesis |
| Description | alpha-lipoic acid-NHS contains a lipoic acid group and a terminal NHS group. The NHS group can participate in reactions with primary amine groups to form amide bonds. | | Uses | α-Lipoic acid-NHS is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | Alkyl/ether | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | alpha-lipoic acid-NHS Preparation Products And Raw materials |
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