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Lipoic acid

Lipoic acid Suppliers list
Company Name: Henan DaKen Chemical CO.,LTD.
Tel: +86-371-55531817
Products Intro: Product Name:Lipoic acid
Purity:99% Package:100g,500g,1KG,10KG,100KG
Company Name: Nanjing Gold Pharmaceutical Technology Co. Ltd.
Tel: 025-84209270 15906146951
Products Intro: Product Name:Lipoic acid
Purity:99% Package:1000KG;;100KG;10KG;5KG;1KG
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: 0371-55170693
Products Intro: Product Name:62-46-4
Purity:0.99 Package:25KG,5KG;1KG;500G
Company Name: Shanghai Zheyan Biotech Co., Ltd.
Tel: 18017610038
Products Intro: Product Name:Lipoic acid
Purity:HPLC>=98% Package:20mg
Company Name: career henan chemical co
Tel: +86-371-86658258
Products Intro: Product Name:Lipoic acid
CAS: 62-46-4
Purity:99% Package:1KG;15USD

Lastest Price from Lipoic acid manufacturers

  • Lipoic acid
  • US $1.00-1.00 / Kg/Bag
  • 2020-05-12
  • CAS:62-46-4
  • Min. Order: 1g
  • Purity: 99%
  • Supply Ability: 50tons
  • Lipoic acid
  • US $0.00 / mg
  • 2020-05-11
  • CAS:62-46-4
  • Min. Order: 5mg
  • Purity: ≥98%(HPLC)
  • Supply Ability: 10 g
  • Lipoic acid
  • US $15.00 / KG
  • 2019-07-06
  • CAS: 62-46-4
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 1000KG
Lipoic acid Basic information
B vitamins Uses
Product Name:Lipoic acid
Synonyms:(R)-LIPOIC ACID;Thioctic;5-(dithiolan-3-yl)pentanoic acid;R-LIPOIC ACID POTASSIUM COMPOUND;6,8-Thioctic acid;6,8-Thiocticacid;6,8-Thiotic acid;6,8-Thioticacid
Product Categories:Miscellaneous;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Inhibitors;Pharmaceutical intermediates;FINE Chemical & INTERMEDIATES;chiral;API;PHARMACEUTICALS
Mol File:62-46-4.mol
Lipoic acid Structure
Lipoic acid Chemical Properties
Melting point 48-52 °C(lit.)
Boiling point 315.2°C (rough estimate)
density 1.2888 (rough estimate)
refractive index 1.5200 (estimate)
Fp >230 °F
solubility Very slightly soluble in water, very soluble in dimethylformamide, freely soluble in methanol.
CAS DataBase Reference62-46-4(CAS DataBase Reference)
NIST Chemistry ReferenceLipoic acid(62-46-4)
Safety Information
WGK Germany 3
MSDS Information
SigmaAldrich English
Lipoic acid Usage And Synthesis
B vitaminsLipoic acid is a class of compounds belonging to the B class vitamins and is the growth factor of yeast and some kinds of microorganisms. It can play the role of coenzyme role in a multi-enzyme system that is responsible for catalyzing the acyl transfer effect in the reaction of oxidative decarboxylation of pyruvate into acetate and oxidative decarboxylation reaction of α-ketoglutarate into succinic acid. Its chemical name is 5-[3-(1,2-dithiol hetero-cycle)] pentanoic acid. The appearance is pale yellow crystals with the molecular weight being 206.33. DL-body: the melting point is 60~61 ℃. L-body (natural products): the melting point is 45~47.5 ℃. Optical rotation [α] D23 + 113 ℃. D-body (natural products): the melting point is 46~48 ℃. Optical rotation [α] D23 + 104 ℃. It is soluble in organic solvents but insoluble in water. It can be used for the prevention and treatment of acute hepatitis, liver cirrhosis, hepatic coma, fatty liver and other diseases. The natural material is found in the liver, kidneys and heart. Synthetic products is obtained through condensation of ethylene and adipic acid mono-ester chloride in the presence of aluminum chloride into chloropropionyl pivaloyl ester, which further has condensation reaction with sulfuric acid, then go through reduction with sodium borohydride and sodium hydroxide hydrolysis, and finally have reaction with thiourea to obtain it.
6,8-lipoic acids can be dissolved in water and can often be presented together with vitamin B1. There are two forms including oxidized and reduced (6,8-dimercapto octanoic acid) types. Inside the body of organisms, some hydrogen group and acyl group can be accepted or transferred through the conversion of these two forms. It can be taken as the coenzyme of the α-keto acid oxidation decarboxylase and hydroxyethyl enzyme and play the role of acyl and hydrogen group transfer during metabolic pathways. Since the human body can synthesize it, no cases of deficiency have been reported before. However, it is indispensable factors for the growth and development of some microorganisms and protozoa. It is rich in liver and yeast.
The above information is edited by the chemicalbook of Dai Xiongfeng.
UsesIt is a kind of B vitamins and can be used for the treatment of acute and chronic hepatitis, cirrhosis, hepatic coma, fatty liver, diabetes, etc.
It can be used as a kind of antioxidants
Chemical PropertiesThioctic acid, 6,8-dithiooctanoic acid
Useshydrogen-transferring cofactor, potentiating anti-oxidant
DefinitionChEBI: A heterocyclic thia fatty acid comprising pentanoic acid with a 1,2-dithiolan-3-yl group at the 5-position.
Definitionlipoic acid: A vitamin of the vitaminB complex. It is one of thecoenzymes involved in the decarboxylationof pyruvate by the enzymepyruvate dehydrogenase. Goodsources of lipoic acid include liverand yeast.
Lipoic acid Preparation Products And Raw materials
Raw materialsEthyl 6,8-dichlorooctanoate-->6,8-dichlorooctanoic acid
Tag:Lipoic acid(62-46-4) Related Product Information
(RS)-a-Lipoic Acid-d5,rac a-Lipoic Acid-d5 S-ALPHA-LIPOIC ACID LIPOIC ACID PA RESIN 1,2-Dithiolane-3-valeramide~DL-6,8-Dithiooctanoic acid amide~alpha-Lipoic acid amide,A-LIPOIC ACID AMIDE (R)-Lipoic Acid Nicotinamide Alphla-Lipoic Acid Tromethamine Salt A-LIPOIC ACID,(+/-)-ALPHA-LIPOIC ACID,ALPHA-LIPOIC ACID,DL-A-LIPOIC ACID,LIPOIC ACID, DL-ALPHA- R-Lipoic Acid Potassium Compund Ethyl 2-(Chlorosulfonyl)acetate Ascoric Acid Folic acid Lipoic acid Hyaluronic acid Citric acid Isovaleric acid DL-ALPHA-LIPOIC ACID REDUCED FORM,DL-ALPHA-LIPOIC ACID, DIHYDRO-,LIPOIC ACID, REDUCED,alpha-Lipoic acid, dihydro-,Lipoic acid, dihydro-,Reduced lipoic acid,DL-a-Lipoic Acid, Dihydro- dithiolane α-Lipoic Acid