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| | N-(m-PEG4)-N'-(PEG2-NHS ester)-Cy5 Basic information |
| | N-(m-PEG4)-N'-(PEG2-NHS ester)-Cy5 Chemical Properties |
| solubility | Soluble in Water, DMSO, DMF, DCM | | form | Solid | | color | Purple to dark purple |
| | N-(m-PEG4)-N'-(PEG2-NHS ester)-Cy5 Usage And Synthesis |
| Description | N-(m-PEG4)-N'-(PEG2-NHS ester)-Cy5 is a cyanine labeled PEG linker with excitation/emmission maximum 649/667 nm containing a NHS ester group, which is an amine reactive group. Hydophilic PEG spacer increases solubility in aqueous media. This reagent can be utilized to produce Cyanine-labeled biomolecules for subsequent use such as in vivo research, and drug design related experiments. | | Uses | N-(m-PEG4)-N'-(PEG2-NHS ester)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | N-(m-PEG4)-N'-(PEG2-NHS ester)-Cy5 Preparation Products And Raw materials |
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