| Company Name: |
Borenpharm Co., Ltd
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| Tel: |
027-65563561 |
| Email: |
sales@borenpharm.com |
| Products Intro: |
Product Name:DBCO-PEG5-Desthiobiotin
CAS:2032788-37-5
Purity:95% HPLC Package:1g; 5g Remarks:2g
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Desthiobiotin-PEG4-DBCO manufacturers
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| | Desthiobiotin-PEG4-DBCO Basic information |
| | Desthiobiotin-PEG4-DBCO Chemical Properties |
| Boiling point | 1013.4±65.0 °C(Predicted) | | density | 1.24±0.1 g/cm3(Predicted) | | pka | 14.93±0.60(Predicted) |
| | Desthiobiotin-PEG4-DBCO Usage And Synthesis |
| Description | DBCO-PEG4-Desthiobiotin is a single-ring, sulfur-free analog of biotin that binds to streptavidin with nearly equal specificity but less affinity than biotin (Kd?= 1011?vs. 1015M, respectively). Consequently, desthiobiotinylated proteins can be eluted readily and specifically from streptavidin affinity resin using mild conditions based on competitive displacement with free biotin. For pull-down experiments with biological samples, this soft-release characteristic of desthiobiotin also helps to minimize co-purification of endogenous biotinylated molecules, which remain bound to streptavidin upon elution of the target protein complexes with free biotin. DBCO is commonly used for copper-free Click Chemistry reactions. |
| | Desthiobiotin-PEG4-DBCO Preparation Products And Raw materials |
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