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Product Name:Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III)
CAS:39916-28-4
Purity:95% Package:25mg
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Shanghai Hongye Biotechnology Co. Ltd
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Product Name:Chlorido[N,N’-disalicylidene-1,2-phenylenediamine]iron(III)
CAS:39916-28-4
Purity:>98% Package:1mg;10mg;50mg;100mg;
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ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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Product Name:Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III)
CAS:39916-28-4
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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Shanghai Yifei Biotechnology Co. , Ltd.
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Product Name:Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III)
CAS:39916-28-4
Purity:95% Package:5mg;10mg;50mg
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TargetMol Chemicals Inc.
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Product Name:Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III)
CAS:39916-28-4
Purity:详情请点击官网 Package:1 mg
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| | Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III) Basic information |
| Product Name: | Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III) | | Synonyms: | Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III);Chlorido[N,N’-disalicylidene-1,2-phenylenediamine]iron(III);(SP-5-13)-chloro[[2,2′-[1,2-phenylenebis[(nitrilo-κN)methylidyne]]bis[phenolato-κO]](2-)]-iron;Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III) | | CAS: | 39916-28-4 | | MF: | C20H14ClFeN2O2 | | MW: | 405.64 | | EINECS: | | | Product Categories: | | | Mol File: | 39916-28-4.mol | ![Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III) Structure](CAS/20211123/GIF/39916-28-4.gif) |
| | Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III) Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMF: 20 mg/ml; DMSO: 14 mg/ml; Ethanol: 0.3 mg/ml; PBS (pH 7.2): Partially soluble | | form | A crystalline solid |
| | Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III) Usage And Synthesis |
| Description | Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III) is an inducer of ferroptosis.1 It induces ferroptosis, but not apoptosis or necroptosis, in NB1 cancer cells when used at a concentration of 3 μM.1 Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III) inhibits proliferation of BJAB, NALM-6, Jurkat, MelHO, and MCF-7 cancer cells (IC50s = 0.07, 2.5, 1.5, 3, and 5 μM, respectively), as well as NALM-6 cells resistant to daunorubicin and vincristine when used at concentrations ranging from 0.04 to 0.125 μM.2 | | References | 1. Sagasser, J., Ma, B., Baecker, D., et al. A new approach in cancer treatment: Discovery of chlorido[N,N’-disalicylidene-1,2-phenylenediamine]iron(III) complexes as ferroptosis inducers J. Med. Chem. 62(17),8053-8061(2019).
2. Lee, S.-Y., Hille, A., Kitanovic, I., et al. [FeIII(salophene)Cl], a potent iron salophene complex overcomes multiple drug resistance in lymphoma and leukemia cells Leuk. Res. 35(3),387-393(2011). |
| | Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III) Preparation Products And Raw materials |
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