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| | 3-(4-Bromophenyl)pyridine Basic information | | Uses |
| | 3-(4-Bromophenyl)pyridine Chemical Properties |
| Melting point | 38.0 to 42.0 °C | | Boiling point | 331.9±17.0 °C(Predicted) | | density | 1.426±0.06 g/cm3(Predicted) | | storage temp. | Inert atmosphere,Room Temperature | | form | powder to lump to clear liquid | | pka | 4.70±0.10(Predicted) | | color | White or Colorless to Light yellow | | InChI | InChI=1S/C11H8BrN/c12-11-5-3-9(4-6-11)10-2-1-7-13-8-10/h1-8H | | InChIKey | FCHUOBPHXDXZBK-UHFFFAOYSA-N | | SMILES | C1=NC=CC=C1C1=CC=C(Br)C=C1 |
| | 3-(4-Bromophenyl)pyridine Usage And Synthesis |
| Uses | 3-(4-bromophenyl)pyridine is used in laboratory research and development and in chemical and pharmaceutical synthesis processes. | | Chemical Properties | Pale yellow liquid | | Synthesis | In a three-necked flask, p-bromoiodobenzene (28 g, 0.1 mol), pyridine-3-boronic acid (12.3 g, 0.1 mol), potassium carbonate (27.2 g, 200 mmol), tetrakis(triphenylphosphine)palladium (0.8 g), tetrahydrofuran (200 ml) and water (50 ml) were added. The reaction mixture was heated to reflux for 5 hours under nitrogen protection. After completion of the reaction, it was cooled to room temperature and filtered to remove insoluble material. The filtrate was purified by column chromatography to give 13 g of 3-(4-bromophenyl)pyridine in 56% yield. | | References | [1] Patent: CN105753849, 2016, A. Location in patent: Paragraph 0056; 0057
[2] Chemistry - A European Journal, 2017, vol. 23, # 60, p. 15089 - 15097
[3] Patent: EP2065378, 2009, A1. Location in patent: Page/Page column 141 |
| | 3-(4-Bromophenyl)pyridine Preparation Products And Raw materials |
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