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| Product Name: | PTIO | | Synonyms: | 2-Phenyl-4,4,5,5-tetramethylimidazoline-3-oxide-1-oxyl)[stablefreeradicalreagentforthesimultaneousdetermin;2-PHENYL-4,4,5,5-TETRAMETHYLIMIDAZOLINE-1-OXYL-3-OXIDE;2-PHENYL-4,4,5,5-TETRAMETHYLIMIDAZOLINE-3-OXIDE-1-OXYL;PTIO (2-PHENYL-4,4,5,5-TETRAMETHYLIMIDAZOLINE-3-OXIDE-1-OXYL);PTIO (=2-Phenyl-4,4,5,5-tetramethylimidazoline-3-oxide-1-oxyl) [Stable free radical reagent for the simultaneous determination of NO and NO2 in the atmosphere];[(2-Phenyl-4,4,5,5-tetramethyl-3-oxylato-4,5-dihydro-1H-imidazole-3-ium)-1-yloxy]radical;[(4,5-Dihydro-2-phenyl-4,4,5,5-tetramethyl-1H-imidazole-3-oxide)-1-yloxy]radical;[[(2-Phenyl-3-oxylato-4,4,5,5-tetramethyl-1H-imidazole-3-ium)-1-yl]oxy]radical | | CAS: | 18390-00-6 | | MF: | C13H17N2O2* | | MW: | 233.29 | | EINECS: | | | Product Categories: | | | Mol File: | 18390-00-6.mol |  |
| Melting point | approximate 86℃ | | storage temp. | 2-8°C | | solubility | soluble in Methanol | | form | Dark blue solid | | color | Blue to Dark blue |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | HS Code | 2933.99.8210 |
| Description | PTIO is an oxidizing reagent that reacts with nitric oxide to form nitric dioxide and corresponding imino nitroxides. It can be used to assay nitric oxide production when examining nitric oxide synthase inhibitory activity. | | Chemical Properties | blue crystals | | Uses | 2-phenyl-4, 4, 5, 5,-tetramethylimidazoline-1-oxyl 3-oxide (PTIO) has been used as a nitric oxide (NO) scavenger. | | Uses | PTIO is a nitric oxide (NO) radical scavenger used to inhibit physiological effects of NO. | | Synthesis Reference(s) | Journal of the American Chemical Society, 90, p. 1078, 1968 DOI: 10.1021/ja01006a053 | | General Description | Nitric oxide radical scavenger. Reacts with nitric oxide in a stoichiometric manner without affecting nitric oxide synthase activity. Inhibits the enhanced vascular permeability in solid tumors. | | Biochem/physiol Actions | Product does not compete with ATP. |
| | PTIO Preparation Products And Raw materials |
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