| Company Name: |
BOC Sciences
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| Tel: |
1-631-485-4226; 16314854226 |
| Email: |
info@bocsci.com |
| Products Intro: |
Product Name:(R)-Aspartimide
CAS:404887-22-5
Purity:>95% Remarks:(R)-Aspartimide is a bioactive byproduct formed during solid-phase peptide synthesis (SPPS) of aspar
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| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:(R)-Aspartimide
CAS:404887-22-5
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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| | 2,5-Pyrrolidinedione, 3-amino-, (3R)- Basic information |
| | 2,5-Pyrrolidinedione, 3-amino-, (3R)- Chemical Properties |
| Boiling point | 337.0±35.0 °C(Predicted) | | density | 1.337±0.06 g/cm3(Predicted) | | pka | 8.93±0.50(Predicted) | | form | A solid |
| | 2,5-Pyrrolidinedione, 3-amino-, (3R)- Usage And Synthesis |
| Description | (R)-Aspartimide is a byproduct formed during solid-phase peptide synthesis (SPPS) of aspartic acid-containing peptides.1 Aspartimide is formed by cyclization of aspartic acid during Fmoc removal or peptide coupling.2 | | References | 1. Ruczyński, J., Lewandowska, B., Mucha, P., et al. Problem of aspartimide formation in Fmoc-based solid-phase peptide synthesis using Dmab group to protect side chain of aspartic acid J. Pept. Sci. 14(3),335-341(2008).
2. Neumann, K., Farnung, J., Baldauf, S., et al. Prevention of aspartimide formation during peptide synthesis using cyanosulfurylides as carboxylic acid-protecting groups Nat. Commun. 11(1),982(2020). |
| | 2,5-Pyrrolidinedione, 3-amino-, (3R)- Preparation Products And Raw materials |
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