Company Name: |
Shaanxi Dideu Newmaterial Co., Ltd.
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Tel: |
029-87576359 15353716720 |
Email: |
1039@dideu.com |
Products Intro: |
Product Name:terofenamate CAS:29098-15-5 Purity:98% Package:25KG
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| terofenamate Basic information |
Product Name: | terofenamate | Synonyms: | 2-(2,6-Dichloro-3-methylphenyl)aminobenzoic acid ethoxymethyl ester;2-[(2,6-Dichloro-3-methylphenyl)amino]benzoic acid ethoxymethyl ester;2-[(2,6-Dichloro-m-tolyl)amino]benzoic acid ethoxymethyl ester;Etoclofene;terofenamate;ethoxymethyl N-(2,6-dichloro-m-tolyl)-anthranilate | CAS: | 29098-15-5 | MF: | C17H17Cl2NO3 | MW: | 0 | EINECS: | 2494344 | Product Categories: | | Mol File: | 29098-15-5.mol | |
| terofenamate Chemical Properties |
Melting point | 73-74° | density | 1.3318 (rough estimate) | refractive index | 1.6140 (estimate) |
Toxicity | LD50 in mice, rats (mg/kg): 918, 307 orally; 300, 274 i.p. (Chieli) |
| terofenamate Usage And Synthesis |
Originator | Etofen Ilfi,Lusofarmaco,Italy,1980 | Manufacturing Process | 10 g sodium salt of N-2,6-dichloro-m-tolylanthranilic acid, 3 ml chloromethyl
ethyl ether and 80 ml dry acetone were refluxed for 12 hours on waterbath
under stirring. The solid was filtered off, and the solution evaporated to
dryness. The residue was dissolved in chloroform, washed with sodium
carbonate solution, then with water until neutral. After drying on sodium
sulfate, the solution was evaporated to dryness. The obtained product was
recrystallized from 95% ethanol. Melting point 73°C to 74°C. | Therapeutic Function | Antiinflammatory, Analgesic |
| terofenamate Preparation Products And Raw materials |
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