| Company Name: |
J & K SCIENTIFIC LTD.
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| Tel: |
010-82848833 400-666-7788 |
| Email: |
jkinfo@jkchemical.com |
| Products Intro: |
Product Name:Etiroxate
CAS:17365-01-4
Package:100Mg,10Mg
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| Company Name: |
Energy Chemical
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| Tel: |
021-58432009 400-005-6266 |
| Email: |
marketing1@energy-chemical.com |
| Products Intro: |
Product Name:Etiroxate
CAS:17365-01-4
Purity:NULL Package:100mg;10mg;25mg;50mg;5mg Remarks:NULL
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| Company Name: |
Foshan Treasure Biotechnology Co., Ltd
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| Tel: |
0757-85921206 18520245316 |
| Email: |
2329783215@qq.com |
| Products Intro: |
Product Name:ETIROXATE
CAS:17365-01-4
Purity:99% HPLC Package:20mg；50mg；100mg；1g
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| | ETIROXATE Basic information |
| Product Name: | ETIROXATE | | Synonyms: | CG-63;DL-a-Methyl-thyroxine Ethyl Ester;O-(4-Hydroxy-3,5-diiodo-phenyl)-3,5-diiodo-a-methyl-DL-tyrosine Ethyl Ester;(±)-2-Amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-2-methylpropionic acid ethyl ester;CG-635;DL-α-Methyl-thyroxine Ethyl Ester;O-(4-Hydroxy-3,5-diiodo-phenyl)-3,5-diiodo-α-methyl-DL-tyrosine Ethyl Ester;ETIROXATE | | CAS: | 17365-01-4 | | MF: | C18H17I4NO4 | | MW: | 818.935 | | EINECS: | | | Product Categories: | Intermediates & Fine Chemicals;Pharmaceuticals | | Mol File: | 17365-01-4.mol |  |
| | ETIROXATE Chemical Properties |
| Melting point | 149-1510C | | Boiling point | 563.7±50.0 °C(Predicted) | | density | 2.321±0.06 g/cm3(Predicted) | | storage temp. | -20°C Freezer | | solubility | DMSO, Methanol | | form | Solid | | pka | 6.89±0.25(Predicted) | | color | Tan |
| | ETIROXATE Usage And Synthesis |
| Chemical Properties | Tan Solid | | Originator | Skleronorm,Gruenenthal,W. Germany,1977 | | Uses | Derivative of thyroxine. Antilipemic. | | Definition | ChEBI: Etiroxate is an aromatic ether. | | Manufacturing Process | 7.91 g of α-methyl thyroxine are suspended in 150 cc of ethanol. While
heating, the solution is saturated with dry hydrogen chloride. Thereafter, the
solvent is distilled off at reduced pressure. The residue is dissolved in a
mixture of ethanol and water (1:1). Adding a 5% solution of sodium hydrogen
carbonate in water, the ethyl ester of α-methyl thyroxine precipitates; melting
point: 156°C to 157°C after recrystallization from ethanol. The yield is 6.05 g,
i.e., 74% of the theoretical yield. | | Therapeutic Function | Antihyperlipoproteinemic |
| | ETIROXATE Preparation Products And Raw materials |
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