cyclic-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine

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Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Company Name: TLC Pharmaceutical Standards Ltd.  
Tel: 18012923235 18012923235
Email: chinasales04@tlcstandards.com.cn
Company Name: Hubei Rhema Reference Materials Technology Co., Ltd.  
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Company Name: TLC Pharmaceutical Standards Ltd.  
Tel: 18012923235
Email: chinasales04@tlcstandards.com.cn
Company Name: TargetMol Chemicals Inc.  
Tel: 13564774135
Email: marketing@targetmol.com

cyclic-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine manufacturers

  • Cyclic HPMPC
  • Cyclic HPMPC pictures
  • $2140.00
  • 2026-05-11
  • CAS:127757-45-3
  • Purity:
  • Supply Ability: 10g
cyclic-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine Basic information
Product Name:cyclic-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine
Synonyms:cyclic-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine;2(1H)-Pyrimidinone, 4-amino-1-[[(5S)-2-hydroxy-2-oxido-1,4,2-dioxaphosphorinan-5-yl]methyl]-;Cyclic HPMPC;Cyclic Cidofovir
CAS:127757-45-3
MF:C8H12N3O5P
MW:261.17
EINECS:
Product Categories:
Mol File:127757-45-3.mol
cyclic-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine Structure
cyclic-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine Chemical Properties
Boiling point 495.6±55.0 °C(Predicted)
density 1.83±0.1 g/cm3(Predicted)
pka2.45±0.40(Predicted)
Safety Information
MSDS Information
cyclic-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine Usage And Synthesis
UsesCyclic HPMPC is a potent antiviral agent. Cyclic HPMPC can increase arterial oxygen saturation levels in lethal vaccinia virus (IHD strain)-infected mice. Cyclic HPMPC improves the outcome of congenital guinea pig cytomegalovirus (GPCMV) infection and decreases viral replication in guinea pig model[1][2].
References[1] Smee DF, et al. Effects of four antiviral substances on lethal vaccinia virus (IHD strain) respiratory infections in mice. Int J Antimicrob Agents. 2004;23(5):430-437. DOI:10.1016/j.ijantimicag.2003.10.010
[2] Bravo FJ, et al. Effect of maternal treatment with cyclic HPMPC in the guinea pig model of congenital cytomegalovirus infection. J Infect Dis. 2006;193(4):591-597. DOI:10.1086/499603
cyclic-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine Preparation Products And Raw materials
Tag:cyclic-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine(127757-45-3) Related Product Information
Cytosine Cidofovir dihydrate CMX 001 2(1H)-Pyrimidinone, 4-amino-1-[[(5S)-2-hydroxy-2-oxido-1,4,2-dioxaphosphorinan-5-yl]methyl]-, hydrate (1:2) Cidofovir Related Compound A (15 mg) (1-[(S)-3-Hydroxy-2-(O-ethylphosphonomethoxy)propyl]cytosine) Antiviral agent 33