Company Name: |
J & K SCIENTIFIC LTD.
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Tel: |
010-82848833 400-666-7788 |
Email: |
jkinfo@jkchemical.com |
Products Intro: |
Product Name:6,7-ADTN hydrobromide CAS:13575-86-5 Package:10mg, 50mg
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Company Name: |
Ascent Scientific
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Tel: |
4401179829988 |
Email: |
customerservice@ascentscientific.co.uk |
Products Intro: |
Product Name:6,7-ADTN hydrobromide CAS:13575-86-5 Purity:>99% Package:10mg;50mg Remarks:Dopamine agonist
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Company Name: |
ChemCell Biomedicine Co.,Ltd.
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Tel: |
020-13556033878 2965585218 13556033878 |
Email: |
chemcell@hotmail.com |
Products Intro: |
Product Name:6-aminotetralin-2,3-diol CAS:13575-86-5 Purity:98% Package:5mg;10mg;20mg;50mg;100mg;250mg;500mg;1g;5g;10g;25g;100g
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| 6-aminotetralin-2,3-diol Basic information |
Product Name: | 6-aminotetralin-2,3-diol | Synonyms: | 6-aminotetralin-2,3-diol;6-Amino-5,6,7,8-tetrahydro-2,3-naphthalenediolhydrobromide;ADTN hydrobromide;6,7-Dihydroxy-2-aminotetraline hydrobromide;(+/-)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthaleneHydrobromide;Aminotetraline hydrobromide, 6,7-Dihydroxy-2- | CAS: | 13575-86-5 | MF: | C10H13NO2 | MW: | 0 | EINECS: | | Product Categories: | Dopamine | Mol File: | 13575-86-5.mol | |
| 6-aminotetralin-2,3-diol Chemical Properties |
Melting point | 270-271 °C | storage temp. | 2-8°C | solubility | Soluble in Water (up to 25 mg/ml) | form | solid | color | Tan | Stability: | Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 1 week. |
| 6-aminotetralin-2,3-diol Usage And Synthesis |
Description | 6,7-ADTN HBr (13575-86-5) is a broad spectrum dopamine receptor agonist.1,2? Demonstrates a marked selectivity for the human dopamine D3 receptor.3 6,7-ADTN and psychostimulants such as cocaine and amphetamine reduce excitatory synaptic transmission in the nucleus accumbens by activating presynaptic dopamine receptors.4 | Uses | (+/-)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene hydrobromide is a dopamine receptor agonist in Tribolium castaneum. | References | 1) List et al. (1982), Striatal binding of 2-amino-6,7-[3H]dihydroxy-1,2,3,4-tetrahydronaphthalene to two dopaminergic sites distinguished by their low and high affinity for neuroleptics; J. Neurosci., 2 895
2) Templeton et al. (1982), Binding of [3H]ADTN to rat striatal membranes; Biochem. Pharmacol., 31 1629
3) Freedman et al. (1994), Expression and pharmacological characterization of the human D3 dopamine receptor; Curr. J. Pharmacol. Exp. Ther., 268 417
4) Nicola et al. (1996), Psychostimulants depress excitatory synaptic transmission in the nucleus accumbens via presynaptic D1-like dopamine receptors; J. Neurosci., 16 1591 |
| 6-aminotetralin-2,3-diol Preparation Products And Raw materials |
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