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| | 3,4-DIHYDROXY-5-METHOXYBENZOIC ACID METHYL ESTER Basic information |
| Product Name: | 3,4-DIHYDROXY-5-METHOXYBENZOIC ACID METHYL ESTER | | Synonyms: | RARECHEM AL BF 0702;M3OMG;Benzoic acid, 3,4-dihydroxy-5-Methoxy-, Methyl ester;Methyl 3-methoxy-4,5-dihydroxybenzoate;3,4-DIHYDROXY-5-METHOXYBENZOIC ACID METHYL ESTER;Tryptophan-007;Bifendate-005;METHYL 3,4-DIHYDROXY-5-METHOXYBENZOATE | | CAS: | 3934-86-9 | | MF: | C9H10O5 | | MW: | 198.17 | | EINECS: | | | Product Categories: | | | Mol File: | 3934-86-9.mol |  |
| | 3,4-DIHYDROXY-5-METHOXYBENZOIC ACID METHYL ESTER Chemical Properties |
| Melting point | 112-113 °C | | Boiling point | 391.7±37.0 °C(Predicted) | | density | 1.337±0.06 g/cm3(Predicted) | | storage temp. | Inert atmosphere,Room Temperature | | pka | 8.21±0.23(Predicted) | | form | Solid | | color | Off-white to yellow |
| | 3,4-DIHYDROXY-5-METHOXYBENZOIC ACID METHYL ESTER Usage And Synthesis |
| Uses | Methyl 3,4-dihydroxy-5-methoxybenzoate is used as intermediates of biphenyl diesters. | | Biological Activity | Methyl 3,4-dihydroxy-5-methoxybenzoate has antioxidant properties that protect neuronal cells from oxidative damage. | | Synthesis | Methyl 3,4-dihydroxy-5-methoxybenzoate is synthesizede by esterified with gallic acid and then etherified with dimethyl sulfate. | | in vivo | Methyl 3-O-methylgallate (M3OMG; 10 and 20 mg/kg, i.p., ) treatment mitigated the NaF-induced oxidative stress through normalization of the level of TBARS, reduced levels of glutathione and by the restoration of the diminished antioxidant enzyme activities[1]. | Animal Model: | Fifty male Wistar rats (8-12 , 7-days old, 200-250 g)[1]. | | Dosage: | 10 and 20 mg/kg. | | Administration: | I.P. for 1 week. | | Result: | Mitigated the NaF-induced oxidative stress through normalization of the level of TBARS, reduced levels of glutathione and by the restoration of the diminished antioxidant enzyme activities. |
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| | 3,4-DIHYDROXY-5-METHOXYBENZOIC ACID METHYL ESTER Preparation Products And Raw materials |
| Raw materials | 1,3-Benzodioxole-5-carboxylic acid, 7-hydroxy-2-oxo--->7-HYDROXY-2,2-DIPHENYL-BENZO[1,3]DIOXOLE-5-CARBOXYLIC ACID METHYL ESTER-->1,3-Benzodioxole-5-carboxylic acid, 2-ethoxy-7-hydroxy-, methyl ester-->METHYL 7-METHOXY-2,2-DIPHENYL-1,3-BENZODIOXOLE-5-CARBOXYLATE-->Gallic acid-->Dimethyl sulfone | | Preparation Products | 1,2-Benzenediol, 3-methoxy-5-(trimethoxymethyl)- |
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