(E,E)-METHYL FARNESOATE

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Products Intro: Product Name:(E,E)-METHYL FARNESOATE
CAS:10485-70-8
Purity:0.99 Package:5KG;1KG
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Products Intro: Product Name:(E,E) Methyl Farnesoate, Methyl-(2E,6E,10E)-3,7,11-triMethyldodecatri-2,6,10-eneoate
CAS:10485-70-8
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Products Intro: Product Name:(E,E) Methyl Farnesoate, Methyl-(2E,6E,10E)-3,7,11-triMethyldodecatri-2,6,10-eneoate
CAS:10485-70-8
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Products Intro: Product Name:methyl farnesoate
CAS:10485-70-8
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Products Intro: Product Name:Methyl farnesoate
CAS:10485-70-8
Purity:99.9% Package:5mg
(E,E)-METHYL FARNESOATE Basic information
Discovery Properties Biological functions Synthesis
Product Name:(E,E)-METHYL FARNESOATE
Synonyms:(2E,6E)-Methyl 3,7,11-trimethyldodeca-2,6,10-trienoate;(E,E) Methyl Farnesoate, Methyl-(2E,6E,10E)-3,7,11-triMethyldodecatri-2,6,10-eneoate;2,6,10-Dodecatrienoic acid, 3,7,11-trimethyl-, methyl ester;Farnesyl methyl ester;Methyl (2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrienoate;methyl (E,E)-farnesate;Methyl 3,7,11-trimethyl-2,6,10-dodecatrienoate;Methyl farnesate
CAS:10485-70-8
MF:C16H26O2
MW:250.38
EINECS:
Product Categories:
Mol File:10485-70-8.mol
(E,E)-METHYL FARNESOATE Structure
(E,E)-METHYL FARNESOATE Chemical Properties
Boiling point 72 °C(Press: 0.1 Torr)
density 0.905±0.06 g/cm3(Predicted)
LogP5.513 (est)
Safety Information
MSDS Information
(E,E)-METHYL FARNESOATE Usage And Synthesis
DiscoveryIn 1987, Laufer and his colleagues first identified methyl farnesoate (MF) from the hemolymph of the spider crab Libinia emarginata as a juvenile hormone (JH)-like factor produced by the mandibular organs (MOs). Since then, MF has been found in more than 35 crustacean species.MF is also found in several insect species, and a species of mite.
Properties MF is lipophilic, and highly soluble in hexane and ethanol.
Biological functionsMF has multiple physiological functions, including the regulation of metabolism, molting, reproduction, behavior, and morphogenesis in crustaceans.It stimulates general protein synthesis and ecdysteroid secretion by the Y-organ, and influences the molting cycle.MF plays a key role in the regulation of crustacean reproduction; it enhances egg production in females, and affects the reproductive morphology and behavior in males.The expression of the vitellogenin (Vg) gene is induced by MF in the hepatopancreas, although FA is more potent than MF for this activity.MF has either a stimulatory or an inhibitory role in metamorphosis, depending on the species and developmental stages.MF functions as a sex determinant and induces the production of male offspring in daphnids and other cladoceran species,and is also involved in predator-induced polyphenisms in Daphnia.
SynthesisMF is synthesized by and secreted from the MOs of crustaceans. Like insect JH, MF is synthesized from acetyl-CoA through the mevalonate pathway and the MF-specific pathway.The farnesoic acid O-methyltransferase (FAMeT) gene has been considered as encoding the enzyme that catalyzes FA to MF in crustaceans.In contrast, in insects MF is synthesized from FA by an enzyme encoded in JHAMT, which belongs to a gene family distinct from FAMeT.Recently, JHAMT homologs were also found in the waterflea Daphnia pulex and a species of mite.Therefore, the relevance of FAMeT and JHAMT in MF synthesis in crustaceans and other arthropods needs to be reassessed.
DefinitionChEBI: A member of the juvenile hormone family of compounds that is the methyl ester of farnesoic acid. Found in several species of crustaceans.
Synthesis Reference(s)Journal of the American Chemical Society, 101, p. 4401, 1979 DOI: 10.1021/ja00509a073
(E,E)-METHYL FARNESOATE Preparation Products And Raw materials
Tag:(E,E)-METHYL FARNESOATE(10485-70-8) Related Product Information
Eicosapentaenoic acid ethyl ester cis-11-Eicosenoic acid LINOLENIC ACID ETHYL CITRAL FARNESAL Methyl geranate (E,E)-METHYL FARNESOATE GERANIC ACID FARNESYL METHYL ETHER prednisolone farnesylate