- R-afatinib
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- $1.00 / 1g
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2019-12-26
- CAS:945553-91-3
- Min. Order: 1g
- Purity: ≥98%
- Supply Ability: g/kg/Ton
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| | R-afatinib Basic information |
| Product Name: | R-afatinib | | Synonyms: | 2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3R)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-;(R,E)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetra-
hydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)
but-2-enamide;(R,E)-N-(4-((3-Chloro-4- fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinozolin- 6-yl)-4-(dimethylamino)but-2-enamide;Afatinib impurity 3/R-afatinib/(2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3R)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide;Afatinib-2;Afatinib Enantiomer;(E)-N-[4-(3-chloro-4-fluoroanilino)-7-[(3R)-oxolan-3-yl]oxyquinazolin-6-yl]-4-(dimethylamino)but-2-enamide;2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3R)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-, (2E)- | | CAS: | 945553-91-3 | | MF: | C24H25ClFN5O3 | | MW: | 485.94 | | EINECS: | | | Product Categories: | | | Mol File: | 945553-91-3.mol |  |
| | R-afatinib Chemical Properties |
| Boiling point | 676.9±55.0 °C(Predicted) | | density | 1.380±0.06 g/cm3(Predicted) | | solubility | DMSO (Slightly), Methanol (Slightly) | | form | Solid | | pka | 11.79±0.43(Predicted) | | color | Pale Beige to Pale Brown |
| | R-afatinib Usage And Synthesis |
| Uses | (2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3R)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide, is an impurity of Afatinib (A355300) an aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder. |
| | R-afatinib Preparation Products And Raw materials |
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