5-(3,5-difluorobenzyl)-1H-indazol-3-amine

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Products Intro:	Product Name:5-(3,5-difluorobenzyl)-1H-indazol-3-amine CAS:1108745-30-7 Purity:98% Package:10MG;50MG;100MG,1G,5G,10G

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Company Name:	Antai Fine Chemical Technology Co.,Limited
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Products Intro:	Product Name:5-(3,5-difluorobenzyl)-1H-indazol-3-amine CAS:1108745-30-7 Purity:0.98 Package:1KG;5KG;25KG

Company Name:	ENBRIDGE PHARMTECH CO., LTD.
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Company Name:	Neostar United (Changzhou) Industrial Co., Ltd.
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Products Intro:	Product Name:5-(3,5-Difluorobenzyl)-1H-indazol-3-amine CAS:1108745-30-7 Purity:0.99 Remarks:1KG,5KG,25KG,200KG

5-(3,5-difluorobenzyl)-1H-indazol-3-amine manufacturers

5-(3,5-difluorobenzyl)-1H-indazol-3-amine Basic information

Product Name:	5-(3,5-difluorobenzyl)-1H-indazol-3-amine
Synonyms:	5-(3,5-difluorobenzyl)-1H-indazol-3-amine;3-Amino-5-(3,5-difluorobenzyl)-1H-indazole;5-(3,5-difluoro-benzyl)-1H-indazol-3-ylamine;5-[(3,5-Difluorophenyl)methyl]-1H-indazol-3-amine;1H-Indazol-3-amine, 5-[(3,5-difluorophenyl)methyl]-;5-(3,5- difluorobenzyl)-1 h- azole-3-amine;(3,5-difluorobenzyl)-1H-indazol-3-amine;5-[(3,5-difluorophenyl)methyl]-1H-indazol-3-amine - [D81383]
CAS:	1108745-30-7
MF:	C14H11F2N3
MW:	259.25
EINECS:
Product Categories:
Mol File:	1108745-30-7.mol

5-(3,5-difluorobenzyl)-1H-indazol-3-amine Chemical Properties

Boiling point	450.7±40.0 °C(Predicted)
density	1.399±0.06 g/cm3(Predicted)
storage temp.	2-8°C(protect from light)
pka	14.82±0.40(Predicted)
Appearance	White to off-white Solid
InChI	InChI=1S/C14H11F2N3/c15-10-4-9(5-11(16)7-10)3-8-1-2-13-12(6-8)14(17)19-18-13/h1-2,4-7H,3H2,(H3,17,18,19)
InChIKey	CZQCRNRCCQSJHD-UHFFFAOYSA-N
SMILES	N1C2=C(C=C(CC3=CC(F)=CC(F)=C3)C=C2)C(N)=N1

Safety Information

HS Code

2933998090

MSDS Information

5-(3,5-difluorobenzyl)-1H-indazol-3-amine Usage And Synthesis

Uses	5-(3,5-difluorobenzyl)-1H-indazol-3-amine is an intermediates of Entrectinib(RXDX-101). Entrectinib (RXDX-101, NMS-E628) is an orally bioavailable pan-TrkA/B/C, ROS1 and ALK inhibitor with IC50 ranging between 0.1 and 1.7 nM. Entrectinib (RXDX-101) induces autophagy.

5-(3,5-difluorobenzyl)-1H-indazol-3-amine Preparation Products And Raw materials

Tag:5-(3,5-difluorobenzyl)-1H-indazol-3-amine(1108745-30-7) Related Product Information

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