2,2,5,7,8-PENTAMETHYL-6-CHROMANOL manufacturers
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| | 2,2,5,7,8-PENTAMETHYL-6-CHROMANOL Basic information |
| Product Name: | 2,2,5,7,8-PENTAMETHYL-6-CHROMANOL | | Synonyms: | 2,2,5,7,8-pentamethyl-1-hydroxychroman;3,4-dihydro-2,2,5,7,8-pentamethyl-2H-1-Benzopyran-6-ol;2,2,5,7,8-PENTAMETHYL-6-CHROMANOL;2,2,5,7,8-PENTAMETHYL-6-HYDROXYCHROMAN;2,2,5,7,8-Pentamethyl-6-chromanolTMC-5;6-Hydroxy-2,2,5,7,8-pentamethylchroman;Chromane C-1;Chromanol C1 | | CAS: | 950-99-2 | | MF: | C14H20O2 | | MW: | 220.31 | | EINECS: | | | Product Categories: | Benzopyrans;Building Blocks;Heterocyclic Building Blocks | | Mol File: | 950-99-2.mol |  |
| | 2,2,5,7,8-PENTAMETHYL-6-CHROMANOL Chemical Properties |
| Melting point | 89-91 °C (lit.) | | Boiling point | 344.3±42.0 °C(Predicted) | | density | 1.034±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO: 250 mg/mL (1134.76 mM) | | form | solid | | pka | 11.41±0.40(Predicted) | | color | White |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | HS Code | 2932990090 |
| | 2,2,5,7,8-PENTAMETHYL-6-CHROMANOL Usage And Synthesis |
| Uses | 2,2,5,7,8-Pentamethyl-6-chromanol is the suitable reagent used for the quantitative analysis of α-tocopherol by plasma-based gas chromatography/tandem mass spectrometry (GC/MS/MS) using a tabletop quadrupole ion trap mass spectrometer. It may be employed as α-tocopherol model compound and on oxidation by t-butyl hydroperoxide in chloroform, in the presence of alcohol, affords 5-alkoxymethyl-2,2,7,8-tetramethyl-6-chromanol. It may be used as internal standard for the determination of α- and γ-tocopherol in the rabbit serum and liver by HPLC. | | General Description | 2,2,5,7,8-Pentamethyl-6-chromanol has been reported as an vitamin E model compound. It undergoes oxidation in presence of various alcohols, ranging from methanol to cholesterol, affords 5-alkoxymethyl-2,2,7,8-tetramethyl-6-chromanols. Antioxidant moiety of vitamin E, 2,2,5,7,8-pentamethyl-6-chromanol (PMCol), is reported to have antiandrogen activity in prostate carcinoma cells. |
| | 2,2,5,7,8-PENTAMETHYL-6-CHROMANOL Preparation Products And Raw materials |
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