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| | SB 222200 Basic information |
| Product Name: | SB 222200 | | Synonyms: | 3-METHYL-2-PHENYL-N-[(1S)-1-PHENYLPROPYL]-4-QUINOLINECARBOXAMIDE;3-Methyl-2-phenyl-N-((1S)-1-phenylpropyl)quinoline-4-carboxamide;SB222200//3-Methyl-2-phenyl-N-[(1S)-1-phenylpropyl]quinoline-4-carboxaMide;(S)-3-METHYL-2-PHENYL-N-(1-PHENYLPROPYL)-4-QUINOLINECARBOXAMIDE;SB 222200;SB-222200; SB222200;CS-1124;4-Quinolinecarboxamide, 3-methyl-2-phenyl-N-[(1S)-1-phenylpropyl]- | | CAS: | 174635-69-9 | | MF: | C26H24N2O | | MW: | 380.48 | | EINECS: | | | Product Categories: | | | Mol File: | 174635-69-9.mol |  |
| | SB 222200 Chemical Properties |
| Melting point | 154℃ | | Boiling point | 553.5±50.0 °C(Predicted) | | density | 1.142 | | storage temp. | Sealed in dry,2-8°C | | solubility | DMSO: ~28 mg/mL, soluble | | pka | 12.88±0.46(Predicted) | | form | solid | | color | light yellow |
| | SB 222200 Usage And Synthesis |
| Uses | 3-Methyl-2-phenyl-N-[(1S)-1-phenylpropyl]-4-quinolinecarboxamide is a chemical agent used in the preparation of acylpiperazinyl-pyrazoles as antagonists to the NK3 receptor as antipsychotics (1,2). | | Definition | ChEBI: 3-methyl-2-phenyl-N-[(1S)-1-phenylpropyl]-4-quinolinecarboxamide is a member of quinolines. | | Biological Activity | Potent and selective non-peptide NK 3 receptor antagonist. K i values are 4.4, >100,000 and 250 nM for human NK 3 , NK 1 and NK 2 receptors respectively. Brain penetrant and active in vivo . | | storage | Store at RT |
| | SB 222200 Preparation Products And Raw materials |
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