3,3',4'-三羟基黄酮
| 中文名称 | 3,3',4'-三羟基黄酮 |
|---|---|
| 中文同义词 | 3,3',4'-三羟基黄酮;化合物 T14036 |
| 英文名称 | 2',3'-DIMETHOXY-3-HYDROXYFLAVONE |
| 英文同义词 | 3',4'-DIHYDROXYFLAVONOL;3,3',4'-TRIHYDROXYFLAVONE;2',3'-DIMETHOXYFLAVONOL;2',3'-DIMETHOXY-3-HYDROXYFLAVONE;4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-3-hydroxy-;2-(3,4-Dihydroxyphenyl)-3-hydroxy-4H-1-benzopyran-4-one;3-Hydroxy-2-(3,4-dihydroxyphenyl)-4H-1-benzopyran-4-one;2-(2,3-Dimethoxyphenyl)-3-hydroxy-4H-chromen-4-one, 2-(2,3-Dimethoxyphenyl)-3-hydroxy-4-oxo-4H-chromene |
| CAS号 | 6068-78-6 |
| 分子式 | C15H10O5 |
| 分子量 | 270.24 |
| EINECS号 | |
| 相关类别 | Di-substituted Flavones |
| Mol文件 | 6068-78-6.mol |
| 结构式 |  |
3,3',4'-三羟基黄酮 性质
| 熔点 | 301-303 °C (decomp)(Solv: methanol (67-56-1)) |
|---|---|
| 沸点 | 508.9±50.0 °C(Predicted) |
| 密度 | 1.579±0.06 g/cm3(Predicted) |
| 储存条件 | 2-8°C |
| 溶解度 | 二甲基亚砜：>15mg/mL |
| 形态 | 粉末 |
| 酸度系数(pKa) | 8.58±0.20(Predicted) |
| 颜色 | 淡黄色至深黄色 |
3',4'-Dihydroxyflavonol (DiOHF) 是一种有效的抗氧化剂，可降低糖尿病大鼠肠系膜动脉中的超氧化物并改善 NO 功能。
3',4'-Dihydroxyflavonol (DiOHF) acutely preserves nitric oxide (NO) activity in the presence of elevated reactive oxygen species (ROS). DiOHF improves NO activity in diabetes by reducing Nox2-dependent superoxide production and preventing eNOS uncoupling to improve endothelial function.
3',4'-Dihydroxyflavonol reduces vascular contraction through Ca
²⁺
desensitization in permeabilized third-order branches of rat mesenteric arteries.