| Company Name: |
GlycoPharm.LLC |
| Tel: |
+86-27-63498076 |
| Email: |
sale@glycolipidpharm.com |
Ac4GalNAl manufacturers
- Ac4GalNAl
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2020-03-26
- CAS:1810852-60-8
- Min. Order: 10mg
- Purity: 97%HPLC
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| | Ac4GalNAl Basic information |
| Product Name: | Ac4GalNAl | | Synonyms: | Ac4GalNAl;Ac4GalNAlk;1,3,4,6-Tetra-O-acetyl-2-(4-pentynoylamino)- 2-deoxy-D-galactopyranose;2-Deoxy-2-[(1-oxo-4-pentyn-1-yl)amino]-1,3,4,6-Tetraacetate-D-galactopyranose-1810852-60-8;[(2R,3R,4R,5R)-3,4,6-triacetyloxy-5-(pent-4-ynoylamino)oxan-2-yl]methyl acetate;Ac4GalNAlk (2-Deoxy-2-pent-4-ynamido-D-galactopyranose 1,3,4,6-tetraacetate) | | CAS: | 1810852-60-8 | | MF: | C19H25NO10 | | MW: | 427.4 | | EINECS: | | | Product Categories: | | | Mol File: | 1810852-60-8.mol |  |
| | Ac4GalNAl Chemical Properties |
| Boiling point | 570.1±50.0 °C(Predicted) | | density | 1.28±0.1 g/cm3(Predicted) | | pka | 12.63±0.70(Predicted) |
| | Ac4GalNAl Usage And Synthesis |
| Uses | Ac4GalNAlk is a weakly alkyne-labeled reagent for metabolic oligosaccharide engineering (MOE) that can be used to detect protein glycosylation. MOE reagents can be activated by cellular biosynthetic machinery into nucleotide sugars, which can be further traced through the introduction of glycoproteins in bioorthogonal chemistry. Ac4GalNAlk promotes nucleotide-sugar biosynthesis and increases bioorthogonal cell surface markers[1]. | | References | [1] Cioce A, et al. Optimization of Metabolic Oligosaccharide Engineering with Ac4GalNAlk and Ac4GlcNAlk by an Engineered Pyrophosphorylase. ACS Chem Biol. 2021 Oct 15;16(10):1961-1967. DOI:10.1021/acschembio.1c00034 |
| | Ac4GalNAl Preparation Products And Raw materials |
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