| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
021-33632979 15002134094 |
| Email: |
marketing@targetmol.com |
| Products Intro: |
Product Name:A6770
CAS:1331754-16-5
Package:1 mg;10 mg;5 mg Remarks: 90+%，具体纯度信息请见官网
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| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
|
| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:A6770
CAS:1331754-16-5
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
|
| Company Name: |
Shanghai Yifei Biotechnology Co. , Ltd.
|
| Tel: |
021-65675885 18964387627 |
| Email: |
customer_service@efebio.com |
| Products Intro: |
Product Name:A6770
CAS:1331754-16-5
Purity:98% Package:500μg;1mg;5mg
|
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| | Ethanone, 1-[5-(hydroxymethyl)-1H-imidazol-2-yl]- Basic information |
| | Ethanone, 1-[5-(hydroxymethyl)-1H-imidazol-2-yl]- Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMF: 30 mg/ml,DMSO: 30 mg/ml,PBS (pH 7.2): 10 mg/ml | | form | A crystalline solid |
| | Ethanone, 1-[5-(hydroxymethyl)-1H-imidazol-2-yl]- Usage And Synthesis |
| Biological Activity | A6770 is an inhibitor of sphingosine-1-phosphate (S1P) lyase.1 It induces accumulation of [3H]sphinganine-1-phosphate ([3H]dhS1P), an S1P lyase substrate, in IT-79MTNC3 cells that endogenously express high levels of S1P lyase (EC50 = <0.01 μM), an effect that is reduced in the presence of vitamin B6 (EC50 = <100 μM). | | References | 1.Ohtoyo, M., Tamura, M., Machinaga, N., et al.Scintillation proximity assay to detect the changes in cellular dihydrosphingosine 1-phosphate levelsLipids51(10)1207-1216(2016) |
| | Ethanone, 1-[5-(hydroxymethyl)-1H-imidazol-2-yl]- Preparation Products And Raw materials |
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