| Company Name: |
Shanghai Tauto Biotech Co., Ltd.
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| Tel: |
021-51320588 |
| Email: |
tauto@tautobiotech.com |
| Products Intro: |
Product Name:GITOXIGENIN(RG)
CAS:545-26-6
Purity:NLT 95% HPLC Package:10Mg;20Mg;50Mg;100Mg to graMs.Not More than tens of graMs. Remarks:ASB-00007236-010
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| Company Name: |
Chengdu Push Bio-Technology Co., Ltd.
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| Tel: |
028-85370565-229 18080489829 |
| Email: |
3004654993@qq.com |
| Products Intro: |
Product Name:Gitoxigenin
CAS:545-26-6
Purity:98.0%（HPLC） Package:5mg
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| | GITOXIGENIN Basic information |
| Product Name: | GITOXIGENIN | | Synonyms: | 16β-Hydroxydigitoxigenin, 3β,14,16β-Trihydroxy-5β,20(22)-cardenolide, 5β,20(22)-Cardenolide-3β,14,16β-triol, 3β,14,16β,21-Tetrahydroxy-20(22)-norcholenic acid lactone;3β,14,16β-Trihydroxy-5β,14β-card-20(22)-enolide;Gitoxigenin,98%;3β,14,16β,21-Tetrahydroxy-20(22)-norcholenic acid lactone;3β,14,16β-Trihydroxy-5β,20(22)-cardenolide;5β,20(22)-Cardenolide-3β,14,16β-triol;3,14,16-trihydroxy-,(3-beta,5-beta,16-beta)-card-20(22)-enolid;3-beta,14,16-beta-trihydroxy-5-beta-card-20(22)-enolid | | CAS: | 545-26-6 | | MF: | C23H34O5 | | MW: | 390.51 | | EINECS: | 208-886-2 | | Product Categories: | | | Mol File: | 545-26-6.mol |  |
| | GITOXIGENIN Chemical Properties |
| Melting point | ~230 °C | | Boiling point | 435.71°C (rough estimate) | | density | 1.0639 (rough estimate) | | refractive index | 1.6120 (estimate) | | storage temp. | −20°C | | pka | 14.56±0.70(Predicted) | | Merck | 13,4445 |
| Hazard Codes | T | | Risk Statements | 23/24/25 | | Safety Statements | 36/37/39-45 | | RIDADR | UN 1544 6.1/PG 1 | | WGK Germany | 3 | | RTECS | FH5391000 | | F | 10 | | HazardClass | 6.1(b) | | PackingGroup | III |
| | GITOXIGENIN Usage And Synthesis |
| Chemical Properties | light yellow flakes | | Uses | Gitoxigenin is a related compound of Digitoxigenin, which has been used in a study to assess its stereochemical effects in cancer cytotoxicity. Digitoxigenin has also been used in a study to investigate the advantage of gold(I)-catalyzed glycosidation of glycosyl o-alkyl benzoates to assemble digitoxin. | | Definition | ChEBI: Gitoxigenin is a 3beta-hydroxy steroid, a 14beta-hydroxy steroid and a 16beta-hydroxy steroid. It derives from a hydride of a 5beta-cardanolide. | | Biochem/physiol Actions | Structure-activity relationships for 16β-substituted digitoxigenins as inhibitors of Na+/K+ ATPases. | | Purification Methods | Recrystallisation of gitoxigenin from aqueous EtOH produces plates of the sesquihydrate which dehydrate on drying at 100o in vacuo. It also recrystallises from Me2CO/MeOH and from EtOAc (the crystals contain 1 mol of EtOAc) with [] D +24.8o (c 1, dioxane). It has UV with max at 310, 485 and 520nm in 96% H2SO4. On heating with ethanolic HCl it yields digitaligenin with loss of H2O. [Smith J Chem Soc 23 1931, Beilstein 8 IV 2456.] |
| | GITOXIGENIN Preparation Products And Raw materials |
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