索托拉西布中间体 基本信息
| 中文名称 | 索托拉西布中间体 |
|---|---|
| 中文同义词 | 索托拉西布中间体;PYRIDO[2,3-D]PYRIMIDINE-2,4(1H,3H)-DIONE, 7-CHLORO-6-FLUORO-1-[4-METHYL-2-(1-METHYLETHYL)-3-PYRIDINY;SOTORASIB中间体;7-氯-6-氟-(1M)-1-[4-甲基-2-(丙烷-2-基)吡啶-3-基]吡啶并[2,3-D]嘧啶-2,4(1H,3H)-二酮;(1R)-7-氯-6-氟-1-(2-异丙基-4-甲基吡啶-3-基)吡啶基[2,3-D]嘧啶-2,4(1H,3H)-二酮 |
| 英文名称 | (1R)-7-Chloro-6-fluoro-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione |
| 英文同义词 | Pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione, 7-chloro-6-fluoro-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]-, (1R)-;7-chloro-6-fluoro-(1M)-1-[4-methyl-2-(propan-2-yl)pyridin-3-yl]pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione;(1R)-7-Chloro-6-fluoro-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione;(1R)-7-Chloro-6-fluoro-1-(2-isopropyl-4-methylpyridin-3-yl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione |
| CAS号 | 2300966-23-6 |
| 分子式 | C16H14ClFN4O2 |
| 分子量 | 348.76 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 2300966-23-6.mol |
| 结构式 |  |
索托拉西布中间体 性质
| 密度 | 1.397±0.06 g/cm3(Predicted) |
|---|---|
| 酸度系数(pKa) | 6.91±0.20(Predicted) |
| InChI | InChI=1S/C16H14ClFN4O2/c1-7(2)11-12(8(3)4-5-19-11)22-14-9(15(23)21-16(22)24)6-10(18)13(17)20-14/h4-7H,1-3H3,(H,21,23,24) |
| InChIKey | OXJTVPMAMRSGNT-UHFFFAOYSA-N |
| SMILES | O=C1NC(=O)C2=CC(F)=C(Cl)N=C2N1C1C(=CC=NC=1C(C)C)C |