| Company Name: |
Asymchem Labs. Gold |
| Tel: |
17347534561 |
| Email: |
liujiaqi11751@asymchem.com.cn |
- ALC-0159
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2026-08-12
- CAS:1849616-42-7
- Min. Order: 1KG
- Purity: 98%
- Supply Ability: 1000kgs
Related articles - What is the use of the ALC-0159?
- ALC-0159 is a polyethylene glycolated lipid that can be used as a vaccine excipient and has been used in the pharmaceutical fi....
- Mar 18，2024
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| Product Name: | ALC-0159 | | Synonyms: | Methoxypoly(ethylene glycol) ditetradecylacetamide;2-[(polyethylene glycol)-2000]-N,N ditetradecylacetamide(ALC- 0159);Poly(oxy-1,2-ethanediyl), α-[2-(ditetradecylamino)-2-oxoethyl]-ω-methoxy-;2-(2-methoxyethoxy)-N,N-ditetradecylacetamide, ammonia salt;Lipid ALC-0159;mPEG-DTA;α-[2-(Ditetradecylamino)-2-oxoethyl]-ω-methoxy-Poly(oxy-1,2-ethanediyl);ALC0159,conjugate,lipid,vaccine,ALC 0159,ALC-0159,inhibit,excipient,Inhibitor | | CAS: | 1849616-42-7 | | MF: | (C2H4O)nC31H63NO2 | | MW: | 0 | | EINECS: | | | Product Categories: | peg | | Mol File: | 1849616-42-7.mol |  |
| | ALC-0159 Chemical Properties |
| solubility | DMF: 10 mg/ml; DMF:PBS (pH 7.2) (1:2): 0.3 mg/ml; DMSO: Slightly Soluble; Ethanol: 1 mg/ml | | form | A solid | | color | White to off-white |
| | ALC-0159 Usage And Synthesis |
| Physical Form | White to Yellow Solid | | Uses | Methoxypoly(ethylene glycol) ditetradecylacetamide can be used in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound. | | Description | ALC-0159 is a PEG/lipid conjugate (i.e. PEGylated lipid), specifically, it is the N,N-dimyristylamide of 2-hydroxyacetic acid, O-pegylated to a PEG chain mass of about 2 kilodaltons (corresponding to about 45-46 ethylene oxide units per molecule of N,N-dimyristyl hydroxyacetamide). It is a non-ionic surfactant by its nature. It has been deployed in the Pfizer-BioNTech SARS-CoV-2 mRNA vaccine that contains the active ingredient tozinameran. | | Uses | ALC-0159, a polyethylene glycol (PEG) lipid conjugate, could be used as vaccine excipient[1]. | | Application | ALC-0159 is a PEG/lipid conjugate (i.e. PEGylated lipid), specifically, it is the N,N-dimyristylamide of 2-hydroxyacetic acid, O-pegylated to a PEG chain mass of about 2 kilodaltons (corresponding to about 45-46 ethylene oxide units per molecule of N,N-dimyristyl hydroxyacetamide). It is a non-ionic surfactant by its nature. | | References | [1] S Moein Moghimi, et al. Allergic Reactions and Anaphylaxis to LNP-Based COVID-19 Vaccines. Mol Ther. 2021 Mar 3;29(3):898-900. DOI:10.1016/j.ymthe.2021.01.030 |
| | ALC-0159 Preparation Products And Raw materials |
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