泮托拉唑钠水合物
| 中文名称 | 泮托拉唑钠水合物 |
|---|---|
| 中文同义词 | 泮托拉唑钠倍半结晶水合物;特卖 【厂家供应】纯天然 泮托拉唑钠水合物;泮托拉唑钠水合物|泮托拉唑钠水合物医药级99%;泮托拉唑钠水合物164579-32-2含量99%;泮托拉唑钠水合物164579-32-2|医药级99%;优质|泮托拉唑钠水合物|医药级99%;泮托拉唑钠水合物1;泮托拉唑钠水合物 |
| 英文名称 | PantoprazoleSodiumSesquihydrate |
| 英文同义词 | Pantoprazole sodium hydrate;1H-Benzimidazole, 5-(difluoromethoxy)-2-(((3,4-dimethoxy-2-pyridinyl)methyl)sulfinyl)-, sodium salt, hydrate (2:3);Unii-6871619Q5x;6-(Difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole sodium salt hydrate (2:2:3);SKF-96022 SODIUM HYDRATE;Pantoprazole sodium sesquihydrate CRS;Pantoprazole for system suitability CRS;BY1023 (sodium hydrate) |
| CAS号 | 164579-32-2 |
| 分子式 | C16H18F2N3NaO5S |
| 分子量 | 425.38 |
| EINECS号 | 1312995-182-4 |
| 相关类别 | 植物提取物;其他科研原料药;医药中间体;医药原料;医药原料 用于消化性溃疡出血;原料药;原料;日用化学品;化学试剂 |
| Mol文件 | 164579-32-2.mol |
| 结构式 |  |
泮托拉唑钠水合物 性质
| 储存条件 | 4°C, protect from light |
|---|---|
| 溶解度 | 易溶于水和乙醇（96%），几乎不溶于己烷。 |
Pantoprazole sodium hydrate (BY1023 sodium hydrate; 1-10000 μM) leads to concentration-dependent increases in endosomal pH in EMT-6 and MCF7 cells.
Pantoprazole sodium hydrate can block exosome release. Pantoprazole sodium hydrate inhibits the activity of V-H
+
-ATPase and impaires the ability of tumour cells (melanomas, adenocarcinomas, and lymphoma cell lines) to acidify the extracellular medium
Pantoprazole sodium hydrate (BY1023 sodium hydrate; 200 mg/kg; IP; once a week for 3 weeks) significantly increases tumor growth delay of MCF-7 xenografts combined with Doxorubicin.
Pantoprazole sodium hydrate (0.3-3 mg/kg, p.o.) dose-dependently decreases both basal acid secretion in pylorus-ligated rats and the stimulated acid secretion induced by mepirizole in acute fistula rats.
| Animal Model: | Mice bearing MCF-7 or A431 xenografts |
| Dosage: | 200 mg/kg |
| Administration: | IP; once a week for 3 weeks; alone or 2 hours before Doxorubicin (6 mg/kg i.v.) |
| Result: |
Showed even greater growth delay of MCF-7 xenografts with Doxorubicin compared with the single-dose combination.
Significantly increased tumor growth delay with a single dose with Doxorubicin. There is no effect on growth delay alone. |
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024/01/25 | HY-17507B | Pantoprazole sodium hydrate | 50 mg | 230元 | |
| 2024/01/25 | HY-17507B | 泮托拉唑钠水合物 Pantoprazole sodium hydrate | 164579-32-2 | 100mg | 350元 |