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Product Name:10-Nitrolinoleate
CAS:774603-04-2
Purity:>=95% Remarks:Reach out to us for more information about custom solutions.
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Product Name:10-Nitrolinoleate
CAS:774603-04-2
Purity:>98%,BR Package:1MG Remarks:MB6154
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Product Name:10-Nitro-9(E)-12(Z)-Octadecadienoic acid
CAS:774603-04-2
Purity:>98% Package:1mg
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BOC Sciences
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Product Name:10-Nitrolinoleate
CAS:774603-04-2
Purity:95% Package:1G;10G;100G Remarks:10-Nitrolinoleate is the product of nitration of linoleate by NO-derived reactive species. Alteratively, nitrolinoleates can act independently of NO/cGMP and PPARγ signaling to suppress neutrophil and
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(9E,12Z)-10-Nitrooctadecadienoic acid manufacturers
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| | (9E,12Z)-10-Nitrooctadecadienoic acid Basic information |
| Product Name: | (9E,12Z)-10-Nitrooctadecadienoic acid | | Synonyms: | (9E,12Z)-10-Nitrooctadecadienoic acid;10-Nitrolinoleic acid;10-Nitrolinoleate;10-Nitro-9Z,12Z-octadecadienoic acid;LELVHAQTWXTCLY-XYWKCAQWSA-N;9,12-Octadecadienoic acid, 10-nitro-, (9E,12Z)-;10-Nitro-9(E)-12(Z)-Octadecadienoic acid;10 Nitrolinoleic acid,10Nitrolinoleic acid | | CAS: | 774603-04-2 | | MF: | C18H31NO4 | | MW: | 325.44 | | EINECS: | | | Product Categories: | | | Mol File: | 774603-04-2.mol |  |
| | (9E,12Z)-10-Nitrooctadecadienoic acid Chemical Properties |
| Boiling point | 452.2±33.0 °C(Predicted) | | density | 1.016±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMF: 30 mg/ml; DMSO: 25 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml | | form | Liquid | | pka | 4.77±0.10(Predicted) | | color | Colorless to light yellow |
| | (9E,12Z)-10-Nitrooctadecadienoic acid Usage And Synthesis |
| Description | 10-Nitrolinoleate is a nitrated fatty acid and a peroxisome proliferator-activated receptor γ (PPARγ) agonist. It is formed from linoleic acid (Item Nos. 90150 | 90150.1 | 21909) upon exposure to acidified nitrite. | | Uses | 10-Nitrolinoleic acid is a potent peroxisome proliferator-activated receptor γ (PPARγ) agonist. 10-Nitrolinoleic acid competes with [3H]Rosiglitazone for binding to PPAR-γ, with an IC50 of 0.22 μM[1]. | | Definition | ChEBI: 10-Nitro-9Z,12Z-octadecadienoic acid is a nitro fatty acid and an octadecadienoic acid. | | IC 50 | PPARγ: 0.22 μM (IC50) | | References | [1] Dunny E, et, al. Stereocontrolled synthesis of the PPAR-gamma agonist 10-nitrolinoleic acid. J Org Chem. 2010 Aug 6;75(15):5334-6. DOI:10.1021/jo1007493 |
| | (9E,12Z)-10-Nitrooctadecadienoic acid Preparation Products And Raw materials |
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