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desmethylazelastine

desmethylazelastine Suppliers list
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Products Intro: Product Name:N-Desmethyl Azelastine
CAS:47491-38-3
Purity:99% Package:5KG;1KG
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Products Intro: Product Name:Azelastine Impurity 6(EP Impurity D)
CAS:53242-89-9_
Purity:99% Package:10mg;25mg;50mg;100mg
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Products Intro: Product Name:N-Desmethyl Azelastine
CAS:47491-38-3
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Company Name: ShenZhen Trendseen Biological Technology Co.,Ltd.
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Products Intro: Product Name:N-DesMethylAzelastine
CAS:47491-38-3
Purity:99% Package:1kg;25kg
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Products Intro: CAS:47491-38-3
Purity:0.99 Package:5KG;1KG
desmethylazelastine Basic information
Product Name:desmethylazelastine
Synonyms:4-[(4-Chlorophenyl)methyl]-2-(hexahydro-1H-azepin-4-yl)-1(2H)-phthalazinone;Demethylazelastine;N-Desmethyl Azelastine;Azelastine Hydrochloride Impurity;4-(p-Chlorobenzyl)-2-[(hexahydro-1H-azepin)-4-yl]phthalazin-1(2H)-one;Azelastin IMP;N-Desmethyl Azelastine (1.0mg/ml in DMSO);Azelastine Impurity 6
CAS:47491-38-3
MF:C21H22ClN3O
MW:367.87
EINECS:
Product Categories:Various Metabolites and Impurities;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals
Mol File:47491-38-3.mol
desmethylazelastine Structure
desmethylazelastine Chemical Properties
Melting point 90-95°C
Boiling point 544.1±60.0 °C(Predicted)
density 1.29±0.1 g/cm3(Predicted)
storage temp. Refrigerator
solubility Chloroform (Slightly), Methanol (Slightly)
form Solid
pka10.49±0.40(Predicted)
color Pale Yellow to Light Yellow
Safety Information
MSDS Information
desmethylazelastine Usage And Synthesis
Chemical PropertiesPale Yellow Solid
UsesThe main phase I metabolites of Azelastine.
in vivo
1.19Pharmacokinetic parameters of desmethylazelastine after a single oral administration of 1.0 mg/kg azelastine hydrochloride in guinea pigs[1].
BloodLung
Cmax (ng/mL)[a]17.62863
Tmax (h)3.0-6.04.0-6.0
Tlag (h)0.250.39
AUC0-24 (ng?h/mL)[a]18028502
t1/2 (h)4.243.90
CL (L/h)0.213
Lung-blood ratio[b]146146
[a] For lung, the unit in grams (g) instead of milliliter (mL). [b] Mean value calculated from all time points.
desmethylazelastine Preparation Products And Raw materials
Tag:desmethylazelastine(47491-38-3) Related Product Information
azelastine hydrochloride N'-(1-Methylazepan-4-yl)benzohydrazine N-DesMethyl Asenapine-d4 N-Desmethyl Asenapine Hydrochloride Ergoline-8-methanol, 10-methoxy-1-methyl-, 5-bromo-3-pyridinecarboxylate (ester), (8β)- (9CI) N-DESMETHYLDANOFLOXACIN N-Desmethyl Zolmitriptan-d3 Alogliptin Related Compound 26 N-Desmethyl Citalopram-d4 Oxalate N-Desmethyl Clomipramine-d3 Hydrochloride N-desmethylApalutamide N-Desmethyl Alosetron N-DESMETHYLCLOMIPRAMINE HYDROCHLORIDE Azelastine-d4 HCl (-)-(R)-Desmethyl Citalopram Oxalate JPDYIRZKEDRQOF-BTJKTKAUSA-N N-DidesMethyl Cariprazine N-Desmethyl Clomipramine N-Glucuronide

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