GLP-1类似物多肽A8SGLP-1
| 中文名称 | GLP-1类似物多肽A8SGLP-1 |
|---|---|
| 中文同义词 | GLP-1类似物多肽A8SGLP-1;606143;GLP-1类似物多肽 |
| 英文名称 | A8SGLP-1 |
| 英文同义词 | A8SGLP-1;A8SGLP-1 (trifluoroacetate salt);Glycinamide, L-histidyl-L-seryl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-α-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-lysylglycyl-L-arginyl-;L-Histidyl-L-seryl-L-alpha-glutamylglycyl-L-threonyl-L-phenyl-alanyl-L-threonyl-L-seryl-L-alpha-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-alpha-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-L-lysyl-L-alpha-glutamyl-L-phenyl-alanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-lysylglycyl-L-arginyl-glycinamide |
| CAS号 | 753024-08-7 |
| 分子式 | C151H229N41O47 |
| 分子量 | 3370.69 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 753024-08-7.mol |
| 结构式 |  |
GLP-1类似物多肽A8SGLP-1 性质
| 密度 | 1.490±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) |
|---|---|
| 溶解度 | DMSO: Sparingly Soluble: 1-10 mg/ml Ethanol: Soluble: =10 mg/mlPBS (pH 7.2): Sparingly Soluble: 1-10 mg/ml |
| 序列 | His-Ser-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-Gly-NH2 |
GLP-1类似物多肽A8SGLP-1 是一种具有口服活性的 GLP-1 类似物，其 8 位丙氨酸被丝氨酸取代。A8SGLP-1 可降低 db/db 小鼠的血糖而不影响其功能。