Myosin modulator 1

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Myosin modulator 1 Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Myosin modulator 1 Basic information
Product Name:Myosin modulator 1
Synonyms:Myosin modulator 1;3(2H)-Quinazolineacetamide, N-[(1R)-1-(5-cyano-3-fluoro-2-pyridinyl)ethyl]-5,6-difluoro-1,4-dihydro-2-oxo-
CAS:3034189-56-2
MF:C18H14F3N5O2
MW:389.33
EINECS:
Product Categories:
Mol File:3034189-56-2.mol
Myosin modulator 1 Structure
Myosin modulator 1 Chemical Properties
Boiling point 648.5±55.0 °C(predicted)
density 1.49±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
pka12.27±0.20(predicted)
Safety Information
MSDS Information
Myosin modulator 1 Usage And Synthesis
UsesMyosin modulator 1 (Compound B141) is a modulator for myosin, that inhibits ATPase in rabbits psoas, porcine atria and in porcine ventricle, with IC25s of 0.42, 0.13 and 3.09 μM, respectively. Myosin modulator 1 regulates systolic cardiac performance in Sprague Dawley rats[1].
References[1] Hawryluk N, et al., 1,4-dihydroquinazolinone compounds and uses thereof. WO2024073426A1.
Myosin modulator 1 Preparation Products And Raw materials
Tag:Myosin modulator 1(3034189-56-2) Related Product Information
1H-Pyrazole-4-carboxamide, N-[(1R)-5-(5-ethyl-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl]-1-methyl- CK-586 W-7 Hydrochloride 4H-Pyrrolo[2,3-b]quinolin-4-one, 1,2,3,3a-tetrahydro-3a-hydroxy-1-(2-methoxy-4-pyridinyl)-6,7-dimethyl-, (3aS)- Mavacamten 2,3-Butanedione monoxime