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| | FMoc-NH-8(ethylene glycol)-acetic acid Basic information |
| Product Name: | FMoc-NH-8(ethylene glycol)-acetic acid | | Synonyms: | FMoc-NH-8(ethylene glycol)-acetic acid;5,8,11,14,17,20,23,26-Octaoxa-2-azaoctacosanedioic acid 1-(9H-fluoren-9-ylmethyl) ester;Fmoc-NH-PEG8-CH2CO2H;Fmoc-PEG8-acetic acid;Fmoc-NH-8(ethylene glycol)-actic acid;FMoc-NH-8(ethylene glycol)-acetic acid ISO 9001：2015 REACH;26-[(9-Fluorenylmethoxycarbonyl)amino]-3,6,9,12,15,18,21,24-octaoxahexacosanoic acid;26-(fluoren-9-ylmethyloxycarbonylamino)-3,6,9,12,15,18,21,24-octaoxahexaeicosanoic acid | | CAS: | 868594-52-9 | | MF: | C33H47NO12 | | MW: | 649.73 | | EINECS: | | | Product Categories: | peg | | Mol File: | 868594-52-9.mol |  |
| | FMoc-NH-8(ethylene glycol)-acetic acid Chemical Properties |
| Boiling point | 773.7±60.0 °C(Predicted) | | density | 1.201±0.06 g/cm3(Predicted) | | solubility | DMSO : 100 mg/mL (153.91 mM; Need ultrasonic) | | form | Oil | | pka | 3.39±0.10(Predicted) |
| | FMoc-NH-8(ethylene glycol)-acetic acid Usage And Synthesis |
| Description | Fmoc-NH-PEG8-CH2COOH is a PEG linker containing an Fmoc-protected amine and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. |
| | FMoc-NH-8(ethylene glycol)-acetic acid Preparation Products And Raw materials |
| Raw materials | 5,8,11,14,17,20,23,26-Octaoxa-2-azaoctacosanoic acid, 28-hydroxy-,9H-fluoren-9-ylmethyl ester-->alpha-Azido-omega-hydroxy octa(ethylene glycol)-->1-AZIDO-3,6,9-TRIOXAUNDECANE-11-OL-->Bis[2-(2-hydroxyethoxy)ethyl] ether |
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