| Company Name: |
Cayman Chemical Company
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| Tel: |
800-364-9897 |
| Email: |
sales@caymanchem.com |
| Products Intro: |
Product Name:Nifurtimox-d4
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| | NifurtiMox-d4 Basic information |
| | NifurtiMox-d4 Chemical Properties |
| solubility | Acetonitrile:
Methanol: (1:1): soluble
DMSO: soluble |
| | NifurtiMox-d4 Usage And Synthesis |
| Uses | Nifurtimox-d4 is the labeled analogue of Nifurtimox (N458800), an Antiprotozoal. Showing anti-Trypanosoma cruzi activity. | | References | [1] JUAN DIEGO MAYA . Trypanosoma cruzi: effect and mode of action of nitroimidazole and nitrofuran derivatives[J]. Biochemical pharmacology, 2003, 65 6: Pages 999-1006. DOI: 10.1016/s0006-2952(02)01663-5
[2] QUHUAN LI. The anti-protozoan drug nifurtimox preferentially inhibits clonogenic tumor cells under hypoxic conditions.[J]. American journal of cancer research, 2017: 1084-1095.
[3] SONIA SANTELIZ. Dipyridamole potentiated the trypanocidal effect of nifurtimox and improved the cardiac function in NMRI mice with acute chagasic myocarditis.[J]. Memorias do Instituto Oswaldo Cruz, 2017, 112 9: 596-608. DOI: 10.1590/0074-02760160499
[4] GISELLE L SAULNIER SHOLLER. Nifurtimox induces apoptosis of neuroblastoma cells in vitro and in vivo.[J]. Journal of Pediatric Hematology/Oncology, 2009, 31 3: 187-193. DOI: 10.1097/mph.0b013e3181984d91 |
| | NifurtiMox-d4 Preparation Products And Raw materials |
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