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MedChemexpress LLC
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021-58955995 |
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| Products Intro: |
Product Name:(+)-Ketoconazole
CAS:142128-59-4
Purity:>98% Package:990RMB/1g
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| | (+)-Ketoconazole Basic information |
| Product Name: | (+)-Ketoconazole | | Synonyms: | ((addition))-Ketoconazole;(+)-Ketoconazol;(+)-R 41400;(+) Ketoconazole,(+)Ketoconazole;Ethanone, 1-[4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]- | | CAS: | 142128-59-4 | | MF: | C26H28Cl2N4O4 | | MW: | 531.43 | | EINECS: | | | Product Categories: | | | Mol File: | 142128-59-4.mol |  |
| | (+)-Ketoconazole Chemical Properties |
| Boiling point | 753.4±60.0 °C(Predicted) | | density | 1.38±0.1 g/cm3(Predicted) | | solubility | ≥25.5 mg/mL in DMSO with gentle warming; insoluble in H2O; insoluble in EtOH | | pka | 6.88±0.12(Predicted) | | form | solid | | color | White to off-white |
| | (+)-Ketoconazole Usage And Synthesis |
| Uses | (+)-Ketoconazole can be used in pharmacological activity and biological study as ketoconazole stereoisomers differentially induce CYP4501A1 in human and mouse hepatoma. Enantiomerically pure isomer of racemic Ketoconazole (K186000). | | Definition | ChEBI: (2R,4S)-ketoconazole is a cis-1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine which dioxolane moiety has (2R,4S)-configuration. It is an enantiomer of a (2S,4R)-ketoconazole. | | Biological Activity | (+)-ketoconazole is an imidazole anti-fungal agent, a cyp3a4 inhibitor. |
| | (+)-Ketoconazole Preparation Products And Raw materials |
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