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| | 1H-INDOLE-3-ACETICACID,1-(3-CHLOROBENZOYL)-5-METHOXY-2-METHYL Basic information |
| Product Name: | 1H-INDOLE-3-ACETICACID,1-(3-CHLOROBENZOYL)-5-METHOXY-2-METHYL | | Synonyms: | 1H-INDOLE-3-ACETICACID,1-(3-CHLOROBENZOYL)-5-METHOXY-2-METHYL;Indometacin Impurity 13;4-Dechloro-3-chloroindomethacin;Indomethacin Impurity 5(Indomethacin EP Impurity E);Indomethacin EP Impurity 13;Indomethacin impurity 4/Indomethacin EP impurity E/2-(1-(3-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)acetic acid;Indomethacin Imp E;2-[1-(3-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid | | CAS: | 807614-94-4 | | MF: | C19H16ClNO4 | | MW: | 357.79 | | EINECS: | | | Product Categories: | | | Mol File: | 807614-94-4.mol |  |
| | 1H-INDOLE-3-ACETICACID,1-(3-CHLOROBENZOYL)-5-METHOXY-2-METHYL Chemical Properties |
| Melting point | 109 - 112oC | | Boiling point | 500.6±50.0 °C(Predicted) | | density | 1.32±0.1 g/cm3(Predicted) | | storage temp. | -20°C Freezer | | solubility | Chloroform (Slightly), Methanol (Slightly) | | pka | 3.96±0.30(Predicted) | | form | Solid | | color | Pale Pink |
| | 1H-INDOLE-3-ACETICACID,1-(3-CHLOROBENZOYL)-5-METHOXY-2-METHYL Usage And Synthesis |
| Uses | 4-Dechloro-3-chloroindomethacin is an impurity of Indomethacin (I641000) which inhibits cyclooxygenase (IC50=0.1uM) selectively over liposygenases (IC50=100uM for 5-,12- and 15-LO). |
| | 1H-INDOLE-3-ACETICACID,1-(3-CHLOROBENZOYL)-5-METHOXY-2-METHYL Preparation Products And Raw materials |
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