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| | Immunoglobulin G,anti-(human carcinoembryonic antigen) (human-mouse monoclonal hMN-14 g-chain), disulfide withhuman-mouse monoclonal hMN-14 k-chain, dimer 製品概要 |
| 化学名: | | | 英語化学名: | Immunoglobulin G,anti-(human carcinoembryonic antigen) (human-mouse monoclonal hMN-14 g-chain), disulfide withhuman-mouse monoclonal hMN-14 k-chain, dimer | | 别名: | Immunoglobulin G,anti-(human carcinoembryonic antigen) (human-mouse monoclonal hMN-14 g-chain), disulfide withhuman-mouse monoclonal hMN-14 k-chain, dimer;Labetuzumab;Research Grade Labetuzumab(DHC21001);IMMU-14|||hMN-14|||IMMU-100;Research Grade Labetuzumab;Labetuzumab (anti-CEACAM5) | | CAS番号: | 219649-07-7 | | 分子式: | | | 分子量: | 0 | | EINECS: | | | カテゴリ情報: | | | Mol File: | Mol File | ![Immunoglobulin G,anti-(human carcinoembryonic antigen) (human-mouse monoclonal hMN-14 g-chain), disulfide withhuman-mouse monoclonal hMN-14 k-chain, dimer]() |
| | Immunoglobulin G,anti-(human carcinoembryonic antigen) (human-mouse monoclonal hMN-14 g-chain), disulfide withhuman-mouse monoclonal hMN-14 k-chain, dimer 物理性質 |
| 外見 | Liquid | | 色 | Colorless to light yellow |
| | Immunoglobulin G,anti-(human carcinoembryonic antigen) (human-mouse monoclonal hMN-14 g-chain), disulfide withhuman-mouse monoclonal hMN-14 k-chain, dimer Usage And Synthesis |
| 使用 | Treatment of colorectal cancer (humanized monoclonal antibody hMN-14 targeting CEA-
positive cancers). | | brand name | CEA-CIDE (Immunomedics). | | in vivo | Labetuzumab (0.5 mg/rat; i.v.; single) inhibits tumor growth in vivo[1]. | Animal Model: | Female nu/nu mice (6 to 8-week-old; inject TT cells)[1]. | | Dosage: | 0.5 mg/rat | | Administration: | Intravenous injection; single (1 day post-tumor cell injection) | | Result: | Significantly delaied growth of tumor, and led to 64%-70% inhibition of tumor size between days 32 and 60. |
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