N-(2-氯乙基)二苄胺盐酸盐
| 中文名称 | N-(2-氯乙基)二苄胺盐酸盐 |
|---|---|
| 中文同义词 | N,N-联苄基-2-氯乙胺盐酸盐;N-(2-氯乙基)二苄胺盐酸盐;二苄氨基氯乙烷盐酸盐;盐酸二苄乃明;N-(2-氯乙基)二苄胺盐酸盐;N-(2-氯乙基)二苄基胺 盐酸盐;N-(2-氯乙基)-苄胺盐酸盐;N,N-二苄基-2-氯乙胺盐酸盐 |
| 英文名称 | N-(2-Chloroethyl)dibenzylamine hydrochloride |
| 英文同义词 | dibenzylchlorethylaminehydrochloride;Dibenamine Hydrochloride N,N-Dibenzylaminoethyl Chloride Hydrochloride N,N-Dibenzyl-2-chloroethylamine Hydrochloride;N-(2-Chloroethyl)dibenzylamine Hydrochloride;DIBENAMINE HYDROCHLORIDE;dibenzyl(2-chloroethyl)ammonium chloride;n-(2-chloroethyl)-dibenzylaminhydrochloride;n-(2-chloroethyl)-n-(phenylmethyl)-benzenemethanaminhydrochloride;N,N-DIBENZYLAMINOETHYLCHLORIDE HYDROCHLORIDE |
| CAS号 | 55-43-6 |
| 分子式 | C16H19Cl2N |
| 分子量 | 296.23 |
| EINECS号 | 200-234-5 |
| 相关类别 | 胺盐;Building Blocks;Chemical Synthesis;Nitrogen Compounds;Organic Building Blocks;Amine Salts;Amine Salts;Nitrogen Compounds;Organic Building Blocks |
| Mol文件 | 55-43-6.mol |
| 结构式 |  |
N-(2-氯乙基)二苄胺盐酸盐 性质
| 熔点 | 190-193 °C(lit.) |
|---|---|
| 沸点 | 449.72°C (rough estimate) |
| 密度 | 1.1507 (rough estimate) |
| 折射率 | 1.6300 (estimate) |
| 储存条件 | Inert atmosphere,Room Temperature |
| 溶解度 | 在甲醇中几乎透明 |
| 形态 | 结晶粉末 |
| 颜色 | 白色至类白色 |
| Merck | 14,2138 |
| InChI | 1S/C16H18ClN.ClH/c17-11-12-18(13-15-7-3-1-4-8-15)14-16-9-5-2-6-10-16;/h1-10H,11-14H2;1H |
| InChIKey | LZXCEBPGNFLHEQ-UHFFFAOYSA-N |
| SMILES | Cl.ClCCN(Cc1ccccc1)Cc2ccccc2 |
| CAS 数据库 | 55-43-6(CAS DataBase Reference) |
| EPA化学物质信息 | N-(2-Chloroethyl)dibenzylamine hydrochloride (55-43-6) |
Dibenamine hydrochloride 是一种竞争和不可逆的肾上腺素能 (b>adrenergic) 阻断剂，可以修饰肾上腺素的药理作用。Dibenamine hydrochloride 对小鼠体内肾上腺素的破坏率显著增加。
IC50: Adrenergic receptor
Dibenamine (100 nM-10 μM) attenuates the degree of cocaine-induced increase in sensitivity to acetylcholine without any effect on acetylcholine-contraction in isolated vas deferens of guinea pig. Additionally, the degree of dibenamine-induced inhibition dependent on the concentration of dibenamine and inversely related to the concentration of cocaine.
Dibenamine hydrochloride (subcutaneous injection; 25 mg/kg; 48 and 24 hr before the administration of CCl4) decreases the CHCl3, levels at 2 and 6 hr by 30-50 percent, but did not appreciably affect the half-life of CHCl3, in the liver.Pretreatment with Dibenamine apparently slows the conversion of Ccl4 to CHCL3.
安全信息
| 提供商 | 语言 |
|---|---|
|
英文
|