E 6130

Request For Quotation
E 6130 Suppliers list
Company Name: Shanghai YuanYe Biotechnology Co., Ltd.  
Tel: 15026964105
Email: 2881489226@qq.com
Company Name: Fan De(Beijing) Biotechnology Co., Ltd.  
Tel: 15911056312
Email: liming@bio-fount.com
Company Name: TargetMol Chemicals Inc.  
Tel: +1-781-999-5354; +1-00000000000
Email: marketing@targetmol.com
Company Name: HANGZHOU CLAP TECHNOLOGY CO.,LTD  
Tel: 86-571-88216897,88216896 13588875226
Email: sales@hzclap.com
Company Name: Chengdu Peter-like Biotechnology Co., Ltd.  
Tel: 18108052721
Email: 2850505130@qq.com

E 6130 manufacturers

  • E6130
  • E6130 pictures
  • $3128.00
  • 2026-05-11
  • CAS:1427058-33-0
  • Purity:
  • Supply Ability: 10g
  • E6130
  • E6130 pictures
  • $3128.00
  • 2025-08-22
  • CAS:1427058-33-0
  • Purity:
  • Supply Ability: 10g
E 6130 Basic information
Product Name:E 6130
Synonyms:E 6130;3-Pyrrolidineacetic acid, 1-[[2-chloro-6-(trifluoromethyl)phenyl]methyl]-3-[[[1-(1-cyclohexen-1-ylmethyl)-4-piperidinyl]amino]carbonyl]-4-methyl-, (3S,4R)-;E-6130,E6130
CAS:1427058-33-0
MF:C28H37ClF3N3O3
MW:556.06
EINECS:
Product Categories:
Mol File:1427058-33-0.mol
E 6130 Structure
E 6130 Chemical Properties
Boiling point 649.2±55.0 °C(Predicted)
density 1.31±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO: ≥ 250 mg/mL (449.59 mM)
pka4.43±0.10(Predicted)
form Solid
color White to off-white
Safety Information
MSDS Information
E 6130 Usage And Synthesis
UsesE6130 is an orally active and highly selective CX3CR1 modulator, that may be effective for treatment of inflammatory bowel disease.
in vivo

E6130 (10 or 30 mg/kg, p.o.) reduces several inflammatory bowel disease-related parameters in a murine CD4+ CD45RBhigh T-cell-transfer colitis model and a murine oxazolone-induced colitis model[1].

References[1] Wakita H, et al. E6130, a Novel CX3C Chemokine Receptor 1 (CX3CR1) Modulator, Attenuates Mucosal Inflammation and Reduces CX3CR1+ Leukocyte Trafficking in Mice with Colitis. Mol Pharmacol. 2017 Nov;92(5):502-509. DOI:10.1124/mol.117.108381
E 6130 Preparation Products And Raw materials
Tag:E 6130(1427058-33-0) Related Product Information
E 6130 NA Immunology/Inflammation Compound Library Pyrrolo[1,2-a]quinoxalin-4(5H)-one,5-[3-[4-(4-chlorophenyl)-1-piperidinyl]propyl]- Clinical Compound Library 1-Pentanol, 2-[[2-amino-5-[[(1S)-1-phenylethyl]thio]thiazolo[4,5-d]pyrimidin-7-yl]amino]-4-methyl-, 1-(dihydrogen phosphate), (2R)-