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| 化学名: | チロフィバン塩酸塩一水和物 | | 英語化学名: | Tirofiban hydrochloride monohydrate | | 别名: | TIROFIBAN, HYDROCHLORIDE HYDRATE;TirofibanHcl142373-60-2/;N-(Butylsulfonyl)-O-[4-(4-piperidynyl)butyl]-L-tyrosine, Hydrochloride Hydrate;(2S)-2-(Butylsulfonylamino)-3-[4-[4-(4-piperidyl)butoxy]phenyl]propanoic acid hydrochloride hydrate;N-(Butylsulfonyl)-O-(4-(4-piperidinyl)butyl)-L-tyrosine monohydrochloride monohydrate;Tirofiban hydrochloride monohydrate;4-(4-Pyridinyl)butanol hydrochloride;L-Tyrosine, N-(butylsulfonyl)-o-(4-(4-piperidinyl)butyl)-, monohydrochloride, monohydrate | | CAS番号: | 150915-40-5 | | 分子式: | C22H39ClN2O6S | | 分子量: | 495.07 | | EINECS: | 682-504-6 | | カテゴリ情報: | Cardiovascular APIs;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;API;150915-40-5 | | Mol File: | 150915-40-5.mol |  |
| 融点 | 135-137°C | | 貯蔵温度 | -20°C | | 溶解性 | DMSO: >12mg/mL at warmed to 60°C | | 外見 | powder | | 色 | white to beige | | 光学活性 (optical activity) | [α]/D -10 to -18° (c=1, MeOH) | | Merck | 14,9464 |
| | チロフィバン塩酸塩一水和物 Usage And Synthesis |
| 外観 | 白色～うすい黄色粉末～結晶 | | 効能 | 血小板凝集抑制薬, 糖タンパクIIb/IIIa受容体拮抗薬 | | 化学的特性 | White Solid | | 使用 | Tirofiban hydrochloride monohydrate has been used as an αIIbβ3 integrin (glycoprotein IIb/IIIa) inhibitor for mouse induced pluripotent stem cell (iPSC) culture. | | 使用 | A specific nonpeptide platelet fibrinogen receptor (GPIIb/IIIa) antagonist. An antithrombotic used in the treatment of unstable angina | | 使用 | Tirofiban is a specific nonpeptide platelet fibrinogen receptor (GPIIb/IIIa) antagonist. Tirofiban is an antithrombotic used in the treatment of unstable angina. | | 定義 | ChEBI: Tirofiban hydrochloride is a hydrochloride. It contains a tirofiban. | | Biochem/physiol Actions | Tirofiban hydrochloride is a potent non-peptide, glycoprotein IIb/IIIa inhibitor. Blocks platelet aggregation and thrombus formation. |
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