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3B Pharmachem (Wuhan) International Co.,Ltd.
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Product Name:(±)-McN 5652;(6R,10bS)-rel-1,2,3,5,6,10b-Hexahydro-6-[4-(Methylthio)phenyl]-pyrrolo[2,1-a]isoquinoline
CAS:96795-89-0
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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| Company Name: |
BOC Sciences
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1-631-485-4226; 16314854226 |
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| Products Intro: |
Product Name:(±)-McN 5652
CAS:96795-89-0
Purity:98% by HPLC Remarks:(±)-McN 5652 is a potent, orally active 5-HT uptake inhibitor. McN-5652 is characterized by exceptionally high potency as an inhibitor of the uptake of serotonin by rat brain synaptosomes in vitro (Ki
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| Company Name: |
EMMX Biotechnology LLC
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888-539-0666 |
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info@emmx.com |
| Products Intro: |
Product Name:(±)-McN 5652
CAS:96795-89-0
Purity:98% HPLC Package:5mg;10mg;25mg;50mg;100mg;250mg;500mg;1g
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| Company Name: |
MedBioPharmaceutical Technology Inc
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021-69568360 18916172912 |
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| Products Intro: |
Product Name:(+/-)-MCN 5652
CAS:96795-89-0
Purity:98% Package:10mg; 50mg Remarks:Medbio
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| | (+/-)-MCN 5652 Basic information |
| Product Name: | (+/-)-MCN 5652 | | Synonyms: | (+/-)-MCN 5652;rel-(6R*,10bS*)-6α*-[4-(Methylthio)phenyl]-1,2,3,5,6,10bβ*-hexahydropyrrolo[2,1-a]isoquinoline;trans-McN-5652;(-)-McN-5652Z;(-)-McN-5652-Z;1,2,3,5,6,10bβ-Hexahydro-6α-[4-(methylthio)phenyl]pyrrolo[2,1-a]isoquinoline;(6S)-1,2,3,5,6,10bβ-Hexahydro-6β-(4-methylthiophenyl)pyrrolo[2,1-a]isoquinoline;(6R,10bS)-rel-1,2,3,5,6,10b-Hexahydro-6-[4-(methylthio)phenyl]-pyrrolo[2,1-a]isoquinoline | | CAS: | 96795-89-0 | | MF: | C19H21NS | | MW: | 295.44 | | EINECS: | | | Product Categories: | | | Mol File: | 96795-89-0.mol |  |
| | (+/-)-MCN 5652 Chemical Properties |
| storage temp. | Store at -20°C | | solubility | <14.77mg/ml in 1eq. HCl; <22.16mg/ml in DMSO |
| | (+/-)-MCN 5652 Usage And Synthesis |
| Uses | McN 5652, (+/-) is a 5-HT uptake inhibitor. | | Definition | ChEBI: (6R,10bS)-6-[4-(methylthio)phenyl]-1,2,3,5,6,10b-hexahydropyrrolo[2,1-a]isoquinoline is a member of isoquinolines. | | Biological Activity | Potent, high affinity serotonin re-uptake inhibitor that is selective in vivo . In vitro, displays moderate selectivity over noradrenalin and dopamine re-uptake (K i values are 0.68, 2.9 and 36.8 nM for inhibition of serotonin, noradrenalin and dopamine uptake respectively in rat brain synaptosomes). Potently potentiates 5-HT-induced effects in vivo following oral administration. Biological activity resides predominantly in (+)-enantiomer. |
| | (+/-)-MCN 5652 Preparation Products And Raw materials |
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