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| 化学名: | 1,2-シクロヘキサンジオン | | 英語化学名: | 1,2-Cyclohexanedione | | 别名: | 1,2-Cyclohexanedione, 98+%;1,2-Cyclohexanedione,97%;1,2-Cyclohexanedione, 98% 10GR;Two1,2-cyclohexylketone;1,2-Cyclohexanedione 97%;1,2-Cyclohexadione;1,2-Dioxocyclohexane;1,2-CYCLOHEXANEDIONE | | CAS番号: | 765-87-7 | | 分子式: | C6H8O2 | | 分子量: | 112.13 | | EINECS: | 212-155-3 | | カテゴリ情報: | C3 to C6Protein Modification;Reagents for arginine modification;Carbonyl Compounds;Ketones;Specific Amino Acid Modification;Ketone;Pharmaceutical intermediate | | Mol File: | 765-87-7.mol |  |
| 主な危険性 | Xi,Xn | | Rフレーズ | 22 | | Sフレーズ | 24/25 | | WGK Germany | 3 | | RTECS 番号 | GV0340000 | | F | 8 | | Hazard Note | Irritant | | TSCA | Yes | | HSコード | 29142990 |
| | 1,2-シクロヘキサンジオン Usage And Synthesis |
| 外観 | 白色/無色～うすい黄色～うすい黄赤色粉末～塊～透明液体 | | 溶解性 | エタノールに溶ける。 | | 用途 | 有機合成原料、アルギニン残基の正荷電マスク剤。 | | 化学的特性 | clear yellow liquid after melting | | 使用 | 1,2-Cyclohexanedione is utilized as a substrate to study enzyme cyclohexane-1,2-dione hydrolase, which is a new tool to degrade alicyclic compounds. It also acts as a specific reagent for arginine residues. | | 使用 | 1,2-Cyclohexanedione have been used as a substrate to study enzyme cyclohexane-1,2-dione hydrolase as a new tool to degrade alicyclic compounds. | | 定義 | ChEBI: Cyclohexane-1,2-dione is a cyclohexanedione carrying oxo substituents at positions 1 and 2. | | 反応性 |
1,2-Cyclohexanedione may effectively occupy vacant coordination sites and thus promote the present cycloisomerization[1]. Tanaka et al. research the catalytic cycloisomerization of 1,6- and 1,7-diynes leading to trienes and vinylpyrroles by using a cationic rhodium(I)/Segphos complex (2.5-10 mol %) and 1,2-cyclohexanedione (100 mol %).
| | Synthesis Reference(s) | Journal of the American Chemical Society, 73, p. 4658, 1951 DOI: 10.1021/ja01154a048
Tetrahedron Letters, 25, p. 603, 1984 DOI: 10.1016/S0040-4039(00)99949-0
The Journal of Organic Chemistry, 39, p. 3295, 1974 DOI: 10.1021/jo00936a034 | | 参考文献 |
[1] Ken Tanaka, Masao Hirano, Yousuke Otake. “Cationic Rhodium(I)/Segphos-Catalyzed Cycloisomerization of 1,6- and 1,7-Diynes in the Presence of 1,2-Cyclohexanedione.” Organic Letters 9 20 (2007): 3953–3956.
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