2-メトキシ-5-[2-[[2-(2-エトキシフェノキシ)エチル]アミノ]プロピル]ベンゼンスルホンアミド·塩酸塩(80223-99-0)

ChemicalBook Optimization Suppliers

名前:	Chemsky（shanghai）International Co.,Ltd.
電話番号:	021-50135380
電子メール:	shchemsky@sina.com

名前:	Sinopharm Chemical Reagent Co,Ltd.
電話番号:	86-21-63210123
電子メール:	sj_scrc@sinopharm.com

名前:	Nanjing Sunlida Biological Technology Co., Ltd.
電話番号:	025-57798810
電子メール:	sales@sunlidabio.com

名前:	Jinan Mingya Medical Technology Co., Ltd.
電話番号:	0531-85828981
電子メール:	864598798@qq.com

2-メトキシ-5-[2-[[2-(2-エトキシフェノキシ)エチル]アミノ]プロピル]ベンゼンスルホンアミド·塩酸塩製品概要

化学名:	2-メトキシ-5-[2-[[2-(2-エトキシフェノキシ)エチル]アミノ]プロピル]ベンゼンスルホンアミド·塩酸塩
英語化学名:	Tamsulosin hydrochloride
别名:	Tamsulosinehydrochloride;Benzenesulfonamide, 5-[2-[[2-(2-ethoxyphenoxy)ethyl]amino]propyl]-2-methoxy-, monohydrochloride (9CI);dl-Tamsulosin hydrochloride;(-)-(R)-5-[2-[2-(2-Ethoxyphenoxy)ethylamino]propyl]-2-methoxybenzenesulfonamide hydrochloride;Tamsulosin hydrochloride;Tamuzosin hydrochloride;EC-617;Racemic Tamsulosin Hydrochloride (50 mg)
CAS番号:	80223-99-0
分子式:	C20H29ClN2O5S
分子量:	444.97
EINECS:
カテゴリ情報:	Intermediates & Fine Chemicals;Isotope Labelled Compounds;Pharmaceuticals
Mol File:	80223-99-0.mol

2-メトキシ-5-[2-[[2-(2-エトキシフェノキシ)エチル]アミノ]プロピル]ベンゼンスルホンアミド·塩酸塩物理性質

融点	254-256 °C
溶解性	DMSO (Slightly), Methanol (Slightly), Water (Slightly)

安全性情報

HSコード

2935909550

MSDS Information

2-メトキシ-5-[2-[[2-(2-エトキシフェノキシ)エチル]アミノ]プロピル]ベンゼンスルホンアミド·塩酸塩 Usage And Synthesis

化学的特性	White to Off-White Solid
使用	Tamsulosin hydrochloride is a specific ;1-adrenoceptor antagonist. Used in the treatment of benign prostatic hypertrophy.
使用	Tamsulosin is a specific α1-adrenoceptor antagonist. Used in the treatment of benign prostatic hypertrophy.
臨床応用	Treatment of benign prostatic hyperplasia
薬物相互作用	Potentially hazardous interactions with other drugs Anaesthetics: enhanced hypotensive effect. Antidepressants: enhanced hypotensive effect with MAOIs. Antifungals: concentration increased by ketoconazole. Avanafil, vardenafil, sildenafil and tadalafil: enhanced hypotensive effect, avoid concomitant use. Beta-blockers: enhanced hypotensive effect; increased risk of first dose hypotensive effect. Calcium-channel blockers: enhanced hypotensive effect; increased risk of first dose hypotensive effect. Diuretics: enhanced hypotensive effect; increased risk of first dose hypotensive effect. Moxisylyte: possibly severe postural hypotension.
代謝	Tamsulosin is metabolised slowly in the liver primarily by the cytochrome P450 isoenzymes CYP2D6 and CYP3A4; it is excreted mainly in the urine as metabolites and some unchanged drug

Tags:80223-99-0