|
ChemicalBook Optimization Suppliers |
| 名前: |
Alfa Aesar |
| 電話番号: |
400-6106006 |
| 電子メール: |
saleschina@alfa-asia.com |
|
| 融点 | 83-86 °C | | 沸点 | 908°C | | 比重(密度) | 1.84 g/mL at 25 °C (lit.) | | 蒸気圧 | 0.001Pa at 25℃ | | 闪点 | 12 °C | | 貯蔵温度 | Inert atmosphere,Room Temperature | | 溶解性 | Methanol (Slightly), Water (Slightly) | | 酸解離定数(Pka) | 4.756[at 20 ℃] | | 外見 | Powder | | 比重 | 1.84 | | 色 | Yellow to brown to gray-green | | 水溶解度 | Soluble in water, alcohol, dilute mineral acids and alkalies. | | Sensitive | Hygroscopic | | Merck | 14,10128 | | InChIKey | DJWUNCQRNNEAKC-UHFFFAOYSA-L | | LogP | -1.28 | | CAS データベース | 557-34-6(CAS DataBase Reference) | | NISTの化学物質情報 | Zinc acetate(557-34-6) | | EPAの化学物質情報 | Zinc acetate (557-34-6) |
| | 二酢酸亜鉛 Usage And Synthesis |
| 外観 | 無色澄明の液体 | | 定義 | 本品は、酢酸(*)の亜鉛塩であり、次の化学式で表される。
参照表示名称：酢酸 | | 溶解性 | 水にやや溶けやすく、エタノールにやや溶けにくい。 | | 化粧品の成分用途 | 皮膚保護剤、殺菌剤、収れん剤 | | 説明 | Zinc acetate (chemical formula: Zn(O2CCH3)2) is a kind of salt commonly existing in the dihydrate form. It appears as colorless solid. It is produced through the reaction between zinc oxide with acetate acid. Given that zinc is an essential element for growth and development of human body, zinc acetate can be used as a dietary supplement for the treatment of zinc deficiency. It plays an important role for the synthesis of cholesterol, protein, and fats. It can also be used as an astringent, styptic and emetic. In industry, it has various kinds of applications including wood preservation, manufacturing of other zinc salts as well as ethylene acetate, being used as a dye mordant, and analytical reagent. | | 化学的特性 | Zinc acetate occurs as white crystalline, lustrous plates with a faint
acetic odor and an astringent taste. | | 物理的性質 | The acetate group is capable of binding to metal ions in a variety of ways through its two oxygen atoms and several connectivities are observed for the various hydrates of zinc acetate. Anhydrous zinc acetate adopts a polymeric structure consisting of zinc coordinated to four oxygen atoms in a tetrahedral environment, each tetrahedron being connected to neighbors by the acetate groups . The acetate ligands are not bidentate. In contrast, most metal diacetates feature metals in octahedral coordination with bidentate acetate groups. In zinc acetate dihydrate the zinc is octahedral, wherein both acetate groups are bidentate.
2 - 5 - Heating pad
Heating Zn(CH3CO2)2 in a vacuum results in loss of acetic anhydride, leaving a residue of ""basic zinc acetate,"" with the formula Zn4O(CH3CO2)6. This cluster compound has the tetrahedral structure shown below. This species closely resembles the corresponding beryllium compound, although it is slightly expanded with Zn-O distances ～1.97 vs ～1.63 Å for Be4O(OAc)6. | | 使用 | Zinc acetate anhydrous is used in the synthesis of layered Zn-arylphosphonates with potential application in sorption, ion exchange or catalysis. It is utilized in the ultrasonic preparation of zinc sulfide nanoparticles coated on silica particles. It is administered orally or parenterally as a nutritional supplement. It finds an application in the field of industries such as wood preservation, manufacturing other zinc salts, polymers, manufacture of ethylene acetate, as a dye mordant, and analytical reagent. It also acts as a plating inhibitor on primary water piping. | | 製造方法 | Zinc acetate is prepared by the reaction of acetic acid with zinc oxide followed by crystallization (crystals of dihydrate obtained): ZnO + 2CH3COOH → (CH3COO)2Zn + H2O. | | 定義 | ChEBI: Zinc acetate is an acetate salt in which the cationic component is zinc(2+). It has a role as an astringent. It is a zinc molecular entity and an acetate salt. | | 主な応用 | Dietary and medicinal applications
Zinc acetate is used as a dietary supplement and in lozenges used to treat the common cold. Zinc acetate alone is thought to be a more effective treatment than zinc gluconate. Zinc acetate can also be used to treat zinc deficiencies. As an oral daily supplement it is used to inhibit the body's absorption of copper as part of the treatment for Wilson's disease. Zinc acetate is also sold as an astringent in the form of an ointment, a topical lotion; or combined with an antibiotic such as erythromycin for the topical treatment of acne. Furthermore Zinc acetate is commonly sold as a topical anti-itch ointment.
Industrial applications
Industrial applications include wood preserving, manufacturing other zinc salts, polymers, manufacture of ethylene acetate, as a dye mordant, and analytical reagent. Zinc acetate is a precursor via a sol-gel route to the transparent semi conductor zinc oxide. Zinc acetate is also used for manufacturing glazers for painting on porcelain; as a reagent in testing for albumin, tannin, phosphate; as cross-linking agents for polymers; in tobacco smoke filters; and as a topical fungicide. | | 調製方法 | Zinc acetate is synthesized by reacting zinc oxide with glacial acetic
acid, with subsequent crystallization, separation by centrifugation,
and drying and milling of the crystals. No organic solvents are used
during the synthesis. | | 燃焼性と爆発性 | Non flammable | | 応用例（製薬） | Zinc acetate has been used as an excipient in a variety of
pharmaceutical formulations including topical gels, lotions, and
solutions, and subcutaneous injections. It has also been investigated
for use in an oral controlled-release formulation for water-soluble
drugs in combination with sodium alginate and xanthan gum.
Therapeutically, zinc acetate has been used in oral capsules for
the treatment of Wilson’s disease. Zinc acetate has also been
demonstrated to be effective as a spermicide in vaginal contraceptives. | | 安全性 | Zinc acetate is used in topical pharmaceutical formulations and
subcutaneous injections, where it is generally regarded as relatively
nontoxic and nonirritant when used as an excipient. However, zinc
acetate is poisonous by intravenous and intraperitoneal routes; it is
also moderately toxic following oral consumption.
Zinc acetate:
LD50 (rat, oral): 2.510 g/kg
LD50 (mouse, IP): 0.057 g/kg | | Veterinary Drugs and Treatments | Zinc sulfate is used systemically as a nutritional supplement in a
variety of species. Oral zinc acetate has been shown to reduce copper
toxicity in susceptible dog breeds (Bedlington Terriers, West
Highland White Terriers) with hepatic copper toxicosis. Zinc therapy
may also be of benefit in the treatment of hepatic fibrosis in
the dog. Zinc sulfate is used topically as an astringent and as a weak
antiseptic both for dermatologic and ophthalmic conditions. | | 貯蔵 | Zinc acetate loses water of hydration above 101℃. Zinc acetate
should be stored in an airtight container in a cool, dry, place. | | 不和合性 | Zinc acetate is incompatible with oxidizing agents, zinc salts, alkalis
and their carbonates, oxalates, phosphates, and sulfides. | | 規制状況(Regulatory Status) | Included in the FDA Inactive Ingredients Database (SC injections;
topical lotions and solutions). Included in medicines licensed in the
UK. | | 参考文献 | https://en.wikipedia.org/wiki/Zinc_acetate
https://pubchem.ncbi.nlm.nih.gov/compound/Zinc_acetate_dihydrate#section=GHS-Classification |
|