| Company Name: |
J & K SCIENTIFIC LTD.
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| Tel: |
010-82848833 400-666-7788 |
| Email: |
jkinfo@jkchemical.com |
| Products Intro: |
Product Name:C12 CeraMide
CAS:74713-60-3
Package:50Mg,5Mg
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N-LAUROYL-D-ERYTHRO-SPHINGOSINE manufacturers
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| | N-LAUROYL-D-ERYTHRO-SPHINGOSINE Basic information |
| | N-LAUROYL-D-ERYTHRO-SPHINGOSINE Chemical Properties |
| Melting point | 70 - 72°C | | Boiling point | 579.38°C (rough estimate) | | density | 0.9777 (rough estimate) | | refractive index | 1.6310 (estimate) | | storage temp. | -20°C | | solubility | Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly, Heated) | | pka | 13.54±0.20(Predicted) | | form | Solid | | color | White to Off-White | | BRN | 1717021 |
| Safety Statements | 24/25 | | WGK Germany | 3 |
| Provider | Language |
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ACROS
| English |
| | N-LAUROYL-D-ERYTHRO-SPHINGOSINE Usage And Synthesis |
| Chemical Properties | white powder | | Uses | C12 Ceramide (d18:1/12:0) or N-lauroyl-D-erythro-sphingosine has been used:
- as a lipid standard in the optimization of the liquid chromatography-mass spectrometry (LC-MS) method conditions
- as an internal standard for lipid extraction in U87MG (human glioma cell line)
- as an internal standard for the quantification of ceramide using liquid chromatography-mass spectrometry (LC-MS) in rat tissues
| | Uses | Ceramide is one of the simplest sphingolipids, consisting of a sphingosine base N-linked to a fatty acid, and is a membrane mediator for cell-signaling events. N-Acyl chain length of membrane ceramides can influence bidimensional transitions, condensed domain morphology, and interfacial thickness. | | Definition | ChEBI: N-dodecanoylsphingosine is a N-acylsphingosine in which the ceramide N-acyl group is specified as dodecanoyl (lauroyl). It is functionally related to a dodecanoic acid. | | General Description | Ceramide is a sphingolipid with long acyl chain attached to a fatty. It is synthesized in the endoplasmic reticulum by ceramide synthase. | | Biochem/physiol Actions | Ceramides?are signaling sphingolipids, which are implicated in regulating stress responses and inflammation. It also regulates cell growth arrest, differentiation and apoptosis. |
| | N-LAUROYL-D-ERYTHRO-SPHINGOSINE Preparation Products And Raw materials |
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