| Company Name: |
Chemsky (shanghai) International Co.,Ltd
|
| Tel: |
021-50135380 |
| Email: |
shchemsky@sina.com |
| Products Intro: |
Product Name:Mepitiostane ;(2α,3α,5α,17β)-2,3-Epithio-17-[(1-Methoxycyclopentyl)oxy]androstane; 2α,3α-Epithio-5α-androstan-17β-yl Methyl Acetal Cyclopentanone;
2α,3α-Epithio-17β-(1-Methoxycyclopentyloxy)-5α-androstane; 2α,3α-Epithio-17β-(cyclopentylMethoxy)-5α-androstane; 2α,3α-Epithio-5α-androstan-17β-yl 1-Methoxycyclopentyl Ether
CAS:21362-69-6
Purity:98+% Package:1Mg;5Mg;10Mg;50Mg;100Mg;500Mg
|
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Email: |
marketing@energy-chemical.com |
| Products Intro: |
Product Name:Mepitiostane
CAS:21362-69-6
Purity:NULL Package:0.5mg;10mg;1mg;5mg Remarks:NULL
|
| Company Name: |
CLEARSYNTH LABS LTD.
|
| Tel: |
+91-22-45045900 |
| Email: |
sales@clearsynth.com |
| Products Intro: |
Product Name:Mepitiostane
CAS:21362-69-6
|
|
| | Mepitiostane Basic information |
| Product Name: | Mepitiostane | | Synonyms: | Mepitiostane;10364S;2,3-Epithio-1H-cyclopenta[a]phenanthrene, androstane deriv.;2a,3a-Epithio-17b-(1-methoxycyclopentyloxy)-5a-androstane;2a,3a-Epithio-17b-(cyclopentylmethoxy)-5a-androstane;2a,3a-Epithio-5a-androstan-17b-yl 1-methoxycyclopentyl ether;5a-Androstane, 2a,3a-epithio-17b-[(1-methoxycyclopentyl)oxy]- (8CI);Androstane, 2,3-epithio-17-[(1-methoxycyclopentyl)oxy]-, (2a,3a,5a,17b)- (9CI) | | CAS: | 21362-69-6 | | MF: | C25H40O2S | | MW: | 404.65 | | EINECS: | | | Product Categories: | Intermediates & Fine Chemicals;Pharmaceuticals;Steroids | | Mol File: | 21362-69-6.mol |  |
| | Mepitiostane Chemical Properties |
| Melting point | 98-101° | | alpha | D20 +22.5 ±0.5° (c = 1 in chloroform) | | Boiling point | 496.21°C (rough estimate) | | density | 0.9998 (rough estimate) | | refractive index | 1.5200 (estimate) | | solubility | Chloroform (Slightly), Ethyl Acetate (Slightly) | | form | Solid | | color | White to Off-White | | Stability: | Acid Sensitive |
| | Mepitiostane Usage And Synthesis |
| Originator | Thioderon,Shionogi,Japan,1979 | | Uses | An orally active anabolic and androgenic steroid. It is a steroidal anti-estrogen with anti-mammary tumor activity. | | Definition | ChEBI: Mepitiostane is an organic molecular entity. | | Manufacturing Process | A mixture of 1.759 g of 2α,3α-epithio-5α-androstan-17β-ol, 2.3 ml of 1- methoxycyclopentene, 20 mg of pyridine salt of p-toluenesulfonic acid and 20 ml of t-butanol is stirred for 4 hours at room temperature. The reaction mixture is poured into an aqueous solution of sodium carbonate and the whole
extracted with dichloromethane. The extract is dried over anhydrous sodium
sulfate and evaporated to remove solvent. Purification of the residue by
chromatography over alumina gives 1.487 g of 17β-(1-methoxycyclopentyl)
oxy-2α,3α-epithio-5α-androstane. Yield 68.2%. MP 98°C to 101°C. | | Therapeutic Function | Antiestrogen |
| | Mepitiostane Preparation Products And Raw materials |
|