| Company Name: |
Shanghai Tauto Biotech Co., Ltd.
|
| Tel: |
021-51320588 |
| Email: |
tauto@tautobiotech.com |
| Products Intro: |
Product Name:Rubratoxin A
CAS:22467-31-8
Purity:NLT 95% HPLC Package:10Mg;20Mg;50Mg;100Mg to graMs.Not More than tens of graMs. Remarks:AG-CN2-0092-C500
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| Company Name: |
Shanghai Hongye Biotechnology Co. Ltd
|
| Tel: |
400-9205774 |
| Email: |
sales@glpbio.cn |
| Products Intro: |
Product Name:Rubratoxin A
CAS:22467-31-8
Purity:>98% Package:1mg;10mg;50mg;100mg;
|
RUBRATOXINA manufacturers
- Rubratoxin A
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- $748.00 / 250μg
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2025-04-30
- CAS:22467-31-8
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | RUBRATOXINA Basic information |
| Product Name: | RUBRATOXINA | | Synonyms: | RUBRATOXINA;10-[(3,6-Dihydro-6-oxo-2H-pyran-2-yl)hydroxymethyl]-4,5,8,9,10,11-hexahydro-4,8-dihydroxy-5-(1-hydroxyheptyl)-1H-cyclonona[1,2-c:5,6-c']difuran-1,3,6-trione;9-[(3,6-Dihydro-6-oxo-2H-pyran-2-yl)hydroxymethyl]-3,4,5,8,9,10-hexahydro-1,5-dihydroxy-4-(1-hydroxyheptyl)-3-oxo-1H-cyclonona[c]furan-6,7-dicarboxylic anhydride;1H-Cyclonona[1,2-c:5,6-c']difuran-1,3,6-trione, 10-[(R)-[(2R)-3,6-dihydro-6-oxo-2H-pyran-2-yl]hydroxymethyl]-4,5,8,9,10,11-hexahydro-4,8-dihydroxy-5-[(1S)-1-hydroxyheptyl]-, (4S,5R,10R)-rel-;Rubratoxin A, PP2A inhibitor | | CAS: | 22467-31-8 | | MF: | C26H32O11 | | MW: | 520.528 | | EINECS: | | | Product Categories: | | | Mol File: | 22467-31-8.mol |  |
| | RUBRATOXINA Chemical Properties |
| Melting point | 210-214℃ (decomposition) | | storage temp. | Store at -20°C | | solubility | Acetonitrile: soluble; DMSO: soluble | | form | A powder | | color | White |
| | RUBRATOXINA Usage And Synthesis |
| Description | Rubratoxin A is a natural mycotoxin and competitive inhibitor of protein phosphatase 2A (PP2A; IC50 = 170 nM). It has no significant effect on several other phosphatases, including PP1, PP2B, and protein tyrosine phosphatase 1B. Rubratoxin A drives overphosphorylation of PP2A substrate proteins in cultured cells treated for three hours at 20 μM. It causes suppression of tumor metastasis and reduction of primary tumor volume in mouse xenografts. | | Uses | Rubratoxin A is a potent and selective competitive PP2A inhibitor. | | storage | -20°C | | References | [1] SHUN-ICHI WADA. Rubratoxin A specifically and potently inhibits protein phosphatase 2A and suppresses cancer metastasis[J]. Cancer Science, 2010, 101 3: 743-750. DOI: 10.1111/j.1349-7006.2009.01438.x |
| | RUBRATOXINA Preparation Products And Raw materials |
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