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| | Pyrimidinetetramine sulfate Basic information |
| Product Name: | Pyrimidinetetramine sulfate | | Synonyms: | pyrimidinetetrayltetraamine sulphate;PYRIMIDINE-2,4,5,6-TETRAMINE SULPHATE;2,4,5,6-TETRAAMINO-PYRIMIDINE SULFATE SALT;2,4,5,6-Tetraaminopyrimidine sulfate hydrate,98%;6-TetraaMinopyriMidine sulfate;PyriMidine-2,4,5,6-tetraaMine sulfate, 95+%;2,4,5,6-tetraMinopyriMide sulfate;2,4,5,6-TetraaMinopyriMidine sulfate hydrate, 98% 25GR | | CAS: | 5392-28-9 | | MF: | C4H10N6O4S | | MW: | 238.22 | | EINECS: | 226-393-0 | | Product Categories: | Building Blocks;C4 to C5;Chemical Synthesis;Heterocyclic Building Blocks;Heterocycle-Pyrimidine series;Aromatics;Heterocycles;Intermediates;Building Blocks;Heterocyclic Building Blocks;FINE Chemical & INTERMEDIATES;Pyrimidines;Amines;(intermediate of methotrexate);bc0001 | | Mol File: | 5392-28-9.mol |  |
| | Pyrimidinetetramine sulfate Chemical Properties |
| | Pyrimidinetetramine sulfate Usage And Synthesis |
| Chemical Properties | Light yellow crystal powder | | Uses | Intermediate in the production of Methotrexate. | | Purification Methods | Purify the salt by recrystallisation from H2O, 2N H2SO4 (20 parts, 67% recovery) or 0.1N H2SO4 (40 parts, 62% recovery), and dried in air. [UV: Konrad & Pfleiderer Chem Ber 103 722 1970, Malletta et al. J Am Chem Soc 69 1814 1947, Cavalieri et al. J Am Chem Soc 70 3875 1948, Beilstein 25 H 423, 25 III/IV 3106.] |
| | Pyrimidinetetramine sulfate Preparation Products And Raw materials |
| Raw materials | 2,4,6-Triaminopyrimidine | | Preparation Products | 6-(Bromomethyl)-2,4-pteridinediamine hydrobromide-->N10-(TRIFLUOROACETYL)PTEROIC ACID-->Pteridine (6CI,7CI,8CI,9CI)-->2,4-DIAMINO-6-(HYDROXYMETHYL)PTERIDINE-->2,4,5,6-TETRAAMINOPYRIMIDINE |
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