|
|
| | Benzyl (2S,3R)-(+)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate Basic information |
| Product Name: | Benzyl (2S,3R)-(+)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate | | Synonyms: | BENZYL (2S,3R)-(+)-6-OXO-2,3-DIPHENYL-4-MORPHOLINECARBOXYLATE;(2S,3R)-benzyl 6-oxo-2,3- diphenylmorpholine-4-carboxylate;4-Morpholinecarboxylic acid, 6-oxo-2,3-diphenyl-, phenylmethyl ester, (2S,3R)-;3-diphenyl-;4-Morpholinecarboxylicacid;6-oxo-2;(2S,3R)-(+)-N-Z-6-oxo-2,3-diphenylMorpholine;(5S,6R)-(+)-4-Benzyloxycarbonyl-5,6-diphenyl-2-Morpholinone | | CAS: | 105228-46-4 | | MF: | C24H21NO4 | | MW: | 387.43 | | EINECS: | | | Product Categories: | Chiral Building Blocks;Heterocyclic Building Blocks;Morpholines | | Mol File: | 105228-46-4.mol |  |
| | Benzyl (2S,3R)-(+)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate Chemical Properties |
| Melting point | 205-207 °C(lit.) | | alpha | 66 º (c=5.5 in methylene chloride) | | Boiling point | 583.5±50.0 °C(Predicted) | | density | 1.242±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | pka | -3.33±0.60(Predicted) | | optical activity | [α]25/D +66°, c = 5.5 in methylene chloride |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-37/39 | | WGK Germany | 3 | | HS Code | 29349990 |
| | Benzyl (2S,3R)-(+)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate Usage And Synthesis |
| Uses | (2S,3R)-(+)-N-Z-6-oxo-2,3-diphenylmorpholine can be used as a starting material for the synthesis of:
- α-Amino-β-silyloxy-ester, a key intermediate for the preparation of antimalarial drug quinine and its analogs.
- R, R-Formylglycine dimethylacetal, a key intermediate for the preparation of tuberculostatic compound capreomycin IB.
- 2R,5R,6S-2-(Methoxycarbonylmethyl)-5,6-diphenylmorpholine hydrochloride, a key intermediate for the preparation of an antibiotic (+)-negamycin.
|
| | Benzyl (2S,3R)-(+)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate Preparation Products And Raw materials |
|