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| 化学名: | コレステロールエステラーゼ | | 英語化学名: | CHOLESTEROL ESTERASE | | 别名: | Cholesterol Esterase from hog pancreas, Sterol-ester acylhydrolase;Cholesterol Esterase from Pseudomonas fluorescens,Sterol-ester acylhydrolase;Cholesterol Esterase from bovine pancreas,Sterol-ester acylhydrolase;Cholesterol esterase froM pseudoMonas sp;Cholesterol Esterase from porcine pancreas,Cholesterol Esterase from hog pancreas, Sterol-ester acylhydrolase;CE (PP), Sterol esterase, sterol-ester acylhydrolase;Cholesterol esterase from porcine pancreas, lyophil.;Cholesterol esterase recombinant, lyophil. | | CAS番号: | 9026-00-0 | | 分子式: | NULL | | 分子量: | 0 | | EINECS: | 232-808-6 | | カテゴリ情報: | enzyme;Enzymes | | Mol File: | Mol File | ![コレステロールエステラーゼ]() |
| | コレステロールエステラーゼ Usage And Synthesis |
| 外観 | 白色〜うすい褐色, 結晶〜粉末又は塊 | | 用途 | 血清中のコレステロールの定量。 | | 化学的特性 | Powder | | 使用 | Cholesterol Esterase from bovine pancreas has been used:
- in γ-oryzanol-hydrolyzing activity
- in cholesterol esterase enzyme activity for quantification of cholesterol and cholesterol esters associated in tear film and lenses samples
- to test in vitro degradation of poly(fumaroyl bioxirane) maleate (PFM) polymer designed for bone tissue engineering
| | 使用 | Cholesterol Esterase from porcine pancreas has been used:
- in an in vitro simulated digestion model to improve the hydrolysis of carotenoid esters in the intestinal phase
- to analyze the bioavailability of phytosterol and cholesterol in the aqueous micellar phase of an in vitro simulated digestion model
- as a standard in enzyme activity assay
| | 使用 | Cholesterol Esterase is used for enzymatic determination of total cholesterol when coupled with cholesterol oxidize in clinical analysis. Cholesterol esterase (CE) is a reversible enzyme that can hydrolyze or synthesize fatty acid esters of cholesterol and other sterols. | | 一般的な説明 | Cholesterol Esterase is a serine hydrolase released from the exocrine pancreas. It belongs to the α/β hydrolase family of enzymes. | | Biochem/physiol Actions | Cholesterol esterase (CE) is a reversible enzyme that can hydrolyze or synthesize fatty acid esters of cholesterol and other sterols. Hydrolysis of water insoluble long chain fatty acid esters requires bile salt activation. Hydrolysis of water soluble esters of short chain fatty acids and lysophospholipids does not require activation by bile salts. It also hydrolyzes tri-, di-, and mono-acylglycerols, phospholipids, lysophospholipids, and ceramides. The enzyme may have multiple functions in lipid and lipoprotein metabolism, as well as in atherosclerosis. Its molecular mass is approximately 129 kDa and the optimum pH range is 7.0-9.0. The enzyme is activated by cholic acid, glycocholic acid, BSA, Mg2+ and 0.3% (v/v) ? X-100. Ag+, Hg2+ and ionic detergents inhibit the activity of the enzyme. |
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