| Company Name: |
TCI (Shanghai) Chemical Trading Co., Ltd.
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| Tel: |
021-61109150 |
| Email: |
sales@tcisct.com |
| Products Intro: |
Product Name:trans-Permethrin D6 (dimethyl D6)
CAS:82523-59-9
Purity:根据客户需求提供 Package:1KG;10KG;100KG;
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| Company Name: |
Reer Technology (Shanghai) Co., LTD
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| Tel: |
021-64400900 15800436310 |
| Email: |
bessey@reertech.com |
| Products Intro: |
Product Name:PERMETHRIN (CIS/TRANS MIX)(D6, 98%) 100 UG/ML IN NONANE
CAS:82523-59-9
Purity:98% Package:1.2 ML Remarks:DLM-10036-1.2
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| Company Name: |
Shanghai Yifei Biotechnology Co. , Ltd.
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| Tel: |
021-65675885 18964387627 |
| Email: |
customer_service@efebio.com |
| Products Intro: |
Product Name:trans-Permethrin-d6 (dimethyl-d6)
CAS:82523-59-9
Purity:95.00% Package:1mg;5mg;10mg
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| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:trans-Permethrin-d6 (dimethyl-d6)
CAS:82523-59-9
Package:1mg;5mg
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TRANS-PERMETHRIN D6 (DIMETHYL D6) manufacturers
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| | TRANS-PERMETHRIN D6 (DIMETHYL D6) Basic information |
| Product Name: | TRANS-PERMETHRIN D6 (DIMETHYL D6) | | Synonyms: | trans-Permethrin D6 ( dimethyl D6), 100 μg /μL in acetone;TRANS-PERMETHRIN D6 (DIMETHYL D6);Permethrin D6;trans-Permethrin D6 (dimethyl D6) 100 μg/mL in Acetone;Permethrin (??????/?????????? mix) (D?, 98%) 100 μg/mL in nonane | | CAS: | 82523-59-9 | | MF: | C21H14Cl2D6O3 | | MW: | 397.329 | | EINECS: | | | Product Categories: | | | Mol File: | 82523-59-9.mol |  |
| | TRANS-PERMETHRIN D6 (DIMETHYL D6) Chemical Properties |
| | TRANS-PERMETHRIN D6 (DIMETHYL D6) Usage And Synthesis |
| Uses | Permethrin-d6 (NRDC-143-d6) is deuterium labeled Permethrin. Permethrin (NRDC-143) is an insecticide, acaricide and a high selectively inhibitor of the Mitochondrial complex I, found in sediment and water samples. Permethrin shows estrogenic in vivo and anti-estrogenic activity in vitro. Permethrin also acts as a neurotoxin affecting neuron membranes by prolonging Sodium channel activation. Permethrin decreases resistance to bacterial infections in medaka (Oryzias latipes)[1][2][3][4][5][6][7]. | | References | [1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. DOI:10.1177/1060028018797110
[2] Xiao X, et al. Exposure to permethrin promotes high fat diet-induced weight gain and insulin resistance in male C57BL/6J mice. Food Chem Toxicol. 2018 Jan;111:405-416. DOI:10.1016/j.fct.2017.11.047
[3] Smith LB, et al. CYP-mediated permethrin resistance in Aedes aegypti and evidence for trans-regulation. PLoS Negl Trop Dis. 2018 Nov 19;12(11):e0006933. DOI:10.1371/journal.pntd.0006933
[4] Shelley LK, et al. Immunotoxic and cytotoxic effects of atrazine, permethrin and piperonyl butoxide to rainbow trout following in vitro exposure[J]. Fish Shellfish Immunol. 2012 Aug;33(2):455-8. DOI:10.1016/j.fsi.2012.05.020
[5] Gassner B, et al. The pyrethroids permethrin and cyhalothrin are potent inhibitors of the mitochondrial complex I[J]. Journal of Pharmacology and Experimental Therapeutics, 1997, 281(2): 855-860. PMID:9152394
[6] Kakko I, et al. The synaptosomal membrane bound ATPase as a target for the neurotoxic effects of pyrethroids, permethrin and cypermethrin[J]. Chemosphere. 2003 May;51(6):475-80. DOI:10.1016/S0045-6535(02)00854-8
[7] Brander SM, et al. The in vivo estrogenic and in vitro anti-estrogenic activity of permethrin and bifenthrin. Environ Toxicol Chem. 2012 Dec;31(12):2848-55. DOI:10.1002/etc.2019
[8] Omotoso G, et al. Permethrin exposure affects neurobehavior and cellular characterization in rats' brain. Environ Anal Health Toxicol. 2020 Dec;35(4):e2020022-0. DOI:10.5620/eaht.2020022 |
| | TRANS-PERMETHRIN D6 (DIMETHYL D6) Preparation Products And Raw materials |
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