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| | Azido-PEG23-amine Basic information |
| Product Name: | Azido-PEG23-amine | | Synonyms: | N3-PEG23-CH2CH2NH2/3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57,60,63,66,69-Tricosaoxahenheptacontan-1-amine,71-azido- | | CAS: | 2172677-19-7 | | MF: | C48H98N4O23 | | MW: | 1099.32 | | EINECS: | | | Product Categories: | | | Mol File: | 2172677-19-7.mol |  |
| | Azido-PEG23-amine Chemical Properties |
| | Azido-PEG23-amine Usage And Synthesis |
| Uses | Azido-PEG23-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG23-amine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | Azido-PEG23-amine Preparation Products And Raw materials |
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